ArticleBMC nephrology2026
Association between food group intakes and metabolic acidosis in patients with non-dialysis-dependent chronic kidney disease.
Article in BMC nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Association between serum bicarbonate and low mid-upper arm circumference in patients with non-dialysis-dependent chronic kidney disease: A cross-sectional study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026Article
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14 authors.
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Abstract
backgroundEvidence is limited regarding the associations between intakes of specific food groups and metabolic acidosis in patients with chronic kidney disease (CKD). We investigated the association between food group-based intakes and metabolic acidosis in patients with non-dialysis-dependent CKD.
methodsWe used baseline data from a prospective cohort study that recruited adult patients with CKD at three hospitals in Tokyo, Japan. Dietary intake was estimated using a validated diet history questionnaire. We examined the association between intakes of individual food groups and serum bicarbonate levels using multiple linear regression, adjusted for demographic and clinical parameters. We also evaluated the association between food group intakes and metabolic acidosis, defined as a serum bicarbonate level < 22 mmol/L, by multiple logistic regression.
resultsAmong the 225 eligible patients (median age 72 years, 33.8% women), 43 patients (19.1%) had metabolic acidosis. Intakes of pulses, green/yellow vegetables (including carrots, tomatoes, and green leafy vegetables), other vegetables (including cabbage, radishes, and onions), and dairy products were positively associated with serum bicarbonate levels. Greater intake of other vegetables was associated with lower odds of metabolic acidosis (highest vs. lowest intake: adjusted odds ratio = 0.28, 95% confidence interval: 0.10, 0.79, P = 0.016); however, such associations were not observed for other food groups, including potatoes, green/yellow vegetables, and pulses.
conclusionsPatients with higher intakes of certain vegetables had lower odds of metabolic acidosis. Further longitudinal studies are warranted to confirm these associations and develop effective dietary measures that optimize the acid-base balance of patients with CKD.
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