ArticleOdontology2026
Tooth discoloration induced by calcium silicate-based cements: effect of dentin surface pre-treatments in regenerative endodontics.
Article in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Comparison of Tooth Discoloration Induced by Mineral Trioxide Aggregate and Polycarboxylate Cement Containing Potassium Nitrate in the Presence and Absence of Blood: An Ex Vivo Study.International journal of dentistry · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This in vitro study evaluated whether dentin bonding agent application or Nd: YAG laser irradiation can reduce tooth discoloration induced by different calcium silicate-based cements (CSCs) under blood-contaminated conditions simulating regenerative endodontic procedures. Ninety extracted human maxillary incisors were standardized and randomly assigned to nine groups (n = 10) according to pre-treatment strategy (no treatment, universal adhesive, or Nd: YAG laser) and CSC type (ProRoot MTA, Biodentine, or TheraCal PT). Following blood application and clot formation, Spongostan and the assigned CSC were placed in the coronal third of the canal. Specimens were restored with resin composite and stored at 37 °C and 100% humidity. Color measurements were performed spectrophotometrically at baseline and after 7, 30, 90, and 180 days. Color changes were calculated using ΔE₀₀ and whiteness index difference (ΔWID) values. Data were analyzed using three-way repeated-measures ANOVA and Sidak post hoc tests (α = 0.05). All groups exhibited time-dependent discoloration. In ProRoot MTA groups, both dentin bonding agent and Nd: YAG laser pre-treatments significantly reduced discoloration compared with untreated controls (p < 0.05), with no significant difference between the two approaches (p > 0.05). Biodentine and TheraCal PT demonstrated significantly greater color stability than ProRoot MTA (p < 0.05). Within the limitations of this study, neither dentin bonding agent nor Nd: YAG laser pre-treatment completely prevented CSC-related discoloration. ProRoot MTA showed the greatest discoloration potential, even after preventive dentin pre-treatment, and therefore may not be the preferred material for anterior regenerative endodontic cases in which esthetics are critical. Biodentine and TheraCal PT demonstrated better color stability and may be more suitable alternatives for esthetically demanding regions, while dentin bonding or Nd: YAG laser pre-treatment appears to provide only limited, material-dependent benefit.
Indexed as
Identifiers
42380707What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.