Evidence map›Paper›PMID 42380665›Full record

ArticleLeukemia2026

Selective targeting of RSK signaling with PMD-026 suppresses FLT3-activated acute myeloid leukemia while sparing normal hematopoiesis.

Gavin M Traber, Kailen Mark, Aarthi Jayanthan, Hee-Don Chae, Minyoung Youn, Jenny Youm, Nick J Sharp, Sandra E Dunn, Kathleen M Sakamoto

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gavin M TraberDivision of Hematology/Oncology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-3494-9196
Kailen MarkDivision of Hematology/Oncology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0009-0004-6990-5761
Aarthi JayanthanPhoenix Molecular Designs, San Diego, CA, USA.
Hee-Don ChaeDivision of Hematology/Oncology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-3159-5329
Minyoung YounDivision of Hematology/Oncology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.
Jenny YoumDivision of Hematology/Oncology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.
Nick J SharpPhoenix Molecular Designs, San Diego, CA, USA.
Sandra E DunnPhoenix Molecular Designs, San Diego, CA, USA.
Kathleen M SakamotoDivision of Hematology/Oncology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA. kmsakamo@stanford.edu.ORCID http://orcid.org/0000-0003-0494-8838

Funding

NRSA Training CoreTL1DK139565 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PHILIP A BEACHY, Chi-yuan Hsu · 2023 to 2026
$5.1M
Investigating and targeting the translational landscape of DBAR01DK136961 · NIDDK · STANFORD UNIVERSITY · PI Maria Barna, Kathleen M Sakamoto · 2024 to 2026
$2.0M
Investigating and targeting the translational landscape of DBAR56DK136961 · NIDDK · STANFORD UNIVERSITY · PI BARNA, MARIA, SAKAMOTO, KATHLEEN M · 2023 to 2023
$150k
NIDDK NIH HHS R01 DK136961NIDDK NIH HHS R56 DK136961NIDDK NIH HHS TL1 DK139565U.S. Department of Defense (United States Department of Defense) HT94252311008U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases) DK136961U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases) TL1DK139565
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42380665
PMCPMC13421334

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.