Evidence map›Paper›PMID 42380628›Full record

ArticleSurgical endoscopy2026

Figure-of-eights vs running suture for fascial closure of large ventral hernias: do figure-of-eights induce ischemia?

William C Bennett, Alvaro C Carvalho, Emerson Lora, Erika M Schmidt, Noah X Tocci, Ashley M Mila-Hoff, Joseph Edwards, Cassandra Hennessy, Luciano G Tastaldi, Lucas R Beffa and 4 more

Abstract readComparative Study
In one paragraph

Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

William C BennettCenter for Abdominal Core Health, Cleveland Clinic Foundation, 2049 E 100th St A Bldg, A10-133, Cleveland, OH, 44195, USA. Bennetw2@ccf.org.ORCID http://orcid.org/0000-0001-8666-5414
Alvaro C CarvalhoCenter for Abdominal Core Health, Cleveland Clinic Foundation, 2049 E 100th St A Bldg, A10-133, Cleveland, OH, 44195, USA.
Emerson LoraCenter for Abdominal Core Health, Cleveland Clinic Foundation, 2049 E 100th St A Bldg, A10-133, Cleveland, OH, 44195, USA.
Erika M SchmidtCenter for Abdominal Core Health, Cleveland Clinic Foundation, 2049 E 100th St A Bldg, A10-133, Cleveland, OH, 44195, USA.
Noah X TocciCenter for Abdominal Core Health, Cleveland Clinic Foundation, 2049 E 100th St A Bldg, A10-133, Cleveland, OH, 44195, USA.
Ashley M Mila-HoffCenter for Abdominal Core Health, Cleveland Clinic Foundation, 2049 E 100th St A Bldg, A10-133, Cleveland, OH, 44195, USA.
Joseph EdwardsCenter for Abdominal Core Health, Cleveland Clinic Foundation, 2049 E 100th St A Bldg, A10-133, Cleveland, OH, 44195, USA.
Cassandra HennessyDepartment of Biostatistics, Vanderbilt University, Nashville, TN, USA.
Luciano G TastaldiCenter for Abdominal Core Health, Cleveland Clinic Foundation, 2049 E 100th St A Bldg, A10-133, Cleveland, OH, 44195, USA.
Lucas R BeffaCenter for Abdominal Core Health, Cleveland Clinic Foundation, 2049 E 100th St A Bldg, A10-133, Cleveland, OH, 44195, USA.
David M KrpataCenter for Abdominal Core Health, Cleveland Clinic Foundation, 2049 E 100th St A Bldg, A10-133, Cleveland, OH, 44195, USA.
Ajita S PrabhuCenter for Abdominal Core Health, Cleveland Clinic Foundation, 2049 E 100th St A Bldg, A10-133, Cleveland, OH, 44195, USA.
Clayton C PetroCenter for Abdominal Core Health, Cleveland Clinic Foundation, 2049 E 100th St A Bldg, A10-133, Cleveland, OH, 44195, USA.
Benjamin T MillerCenter for Abdominal Core Health, Cleveland Clinic Foundation, 2049 E 100th St A Bldg, A10-133, Cleveland, OH, 44195, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMany techniques can reapproximate fascia during herniorrhaphy. Reports suggest utility of interrupted figure-of-eights for large defects less amenable to running suture closures. However, anecdotal concerns regarding 'ischemic' qualities of figure-of-eights may dissuade utilization, despite no substantiating evidence. This study compares wound morbidity for figure-of-eights vs running sutures for fascial closure during open ventral hernia repair (VHR).

methodsA prospectively maintained hernia-specific registry was queried for open VHRs from 1/1/2014 to 12/31/2023 with fascial closure, ≥ 10 cm defect width, CDC Class 1 wound, fascial closure via figure-of-eights or running suture, and clinical follow-up at 30 days. Cases featuring anterior myofascial or cutaneous flaps were excluded. Surgical site occurrence (SSO), surgical site infection (SSI), SSO/SSI requiring procedural intervention (SSO/I-PI), recurrence, and patient-reported quality-of-life (QoL) at 30-day and 1-year intervals were considered. SSO at 30 days was selected as the primary outcome to serve as a surrogate for suture line ischemia, and 1-year recurrence was a key secondary outcome of interest. Baseline factors including age, BMI, gender, race, ASA class, immunosuppressant use, smoking, diabetes, hernia width, and hernia length were controlled via multivariable regression.

resultsA total 4195 cases met criteria and 31% utilized figure-of-eights (n = 1317). Multivariable logistic regression found no increased risk of 30-day SSO or 1-year recurrence for figure-of-eight vs running suture closure. Adjusted odds of SSI (OR 1.47; 95% CI 1.11, 1.95) and SSO/I-PI (OR 1.31; 1.02, 1.70) were greater for figure-of-eight closures. No associations were identified regarding patient-reported QoL or 1-year outcomes.

conclusionsThis retrospective analysis of wound morbidity in clean cases identified an increased risk of SSI and SSO/I-PI for figure-of-eight closures at 30 days vs running closures. Though the association may relate to residual confounding from selective utilization in high complexity repairs rather than an ischemic nature, the results suggest figure-of-eights should perhaps be reserved for challenging or high-tension fascial reapproximation.

Indexed as

FasciotomyHernia, VentralHerniorrhaphyIschemiaSuture TechniquesAgedFemaleHumansMaleMiddle AgedQuality of LifeRecurrenceSurgical Wound InfectionSuturesFascial closureFigure-of-eightHerniorrhaphyRunning sutureVentral hernia repair

Identifiers

PMID42380628
PMCPMC13457274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.