Evidence map›Paper›PMID 42380627›Full record

ArticleSurgical endoscopy2026

Bifurcate peroral endoscopic myotomy for the treatment of achalasia with large epiphrenic esophageal diverticulum (with video).

Ruide Liu, Yuhang Zhang, Huan Jiang, Hao Yang, Lulu Zhang, Shuying Zhou, Bing Hu, Xianglei Yuan, Yi Mou

Abstract readVideo-Audio Media
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In one paragraph

Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ruide Liu *Department of Gastroenterology and Hepatology, Digestive Endoscopy Medical Engineering Research Laboratory, West China Hospital, Sichuan University, No.37, Guo Xue Alley, Wuhou District, Chengdu City, 610041, Sichuan Province, China.
Yuhang Zhang *Department of Gastroenterology and Hepatology, Digestive Endoscopy Medical Engineering Research Laboratory, West China Hospital, Sichuan University, No.37, Guo Xue Alley, Wuhou District, Chengdu City, 610041, Sichuan Province, China.
Huan JiangDepartment of Gastroenterology and Hepatology, Digestive Endoscopy Medical Engineering Research Laboratory, West China Hospital, Sichuan University, No.37, Guo Xue Alley, Wuhou District, Chengdu City, 610041, Sichuan Province, China.
Hao YangWest China School of Medicine, Sichuan University, Chengdu, China.
Lulu ZhangCollege of Foreign Languages and Cultures, Sichuan University, Chengdu, China.
Shuying ZhouZizhong County People's Hospital, Zigong, China.
Bing HuDepartment of Gastroenterology and Hepatology, Digestive Endoscopy Medical Engineering Research Laboratory, West China Hospital, Sichuan University, No.37, Guo Xue Alley, Wuhou District, Chengdu City, 610041, Sichuan Province, China. hubing@wchscu.edu.cn.ORCID http://orcid.org/0009-0007-2272-747X
Xianglei YuanDepartment of Gastroenterology and Hepatology, Digestive Endoscopy Medical Engineering Research Laboratory, West China Hospital, Sichuan University, No.37, Guo Xue Alley, Wuhou District, Chengdu City, 610041, Sichuan Province, China. yuanxianglei@wchscu.edu.cn.
Yi MouDepartment of Gastroenterology and Hepatology, Digestive Endoscopy Medical Engineering Research Laboratory, West China Hospital, Sichuan University, No.37, Guo Xue Alley, Wuhou District, Chengdu City, 610041, Sichuan Province, China. 125654639@qq.com.

Funding

1·3·5 project for disciplines of excellence-Clinical Research Fund, West China Hospital, Sichuan University 2024HXFH033Postdoctor Research Fund of West China Hospital, Sichuan University 2024HXBH164Sichuan Province cadres health research ZH2024-102Sichuan Science and Technology Program 2025ZNSFSC1687
6 · The paper itself

Abstract

backgroundPeroral endoscopic myotomy (POEM) and diverticular POEM (D-POEM) are important treatments for achalasia and esophageal diverticulum, respectively. Herein, we report the clinical outcomes and long-term effectiveness of bifurcate POEM (B-POEM) for patients with simultaneous achalasia and large epiphrenic esophageal diverticulum (EED), a novel technique combining POEM and D-POEM.

methodsWe retrospectively collected patients who underwent B-POEM for achalasia and large EED between January 2019 and December 2023. Clinical success was defined as a postoperative Eckardt score of ≤ 3 without additional intervention until the final follow-up in June 2025.

results11 patients who underwent B-POEM were included. The mean diverticular diameter was 67.0 (standard deviation, SD 10.0; range 48.0-83.0) mm, and the mean location was 35.0 (SD 3.4) centimeters from the incisors. The most common achalasia was type I (n = 4, 36.4%). All B-POEM procedures were successful, and the mean procedure time was 81.5 (SD 11.8) min. The mean preoperative Eckardt score was 5.9 (SD 1.3), which significantly decreased to 1.3 (SD 1.0, P < 0.001) at a median follow-up of 28.0 (range 21.0-80.0) months. No cases received additional endoscopic or surgical intervention.

conclusionsB-POEM was an effective and safe procedure for patients with achalasia and large EED, which needed further prospective study.

Indexed as

Diverticulum, EsophagealEsophageal AchalasiaEsophagoscopyMyotomyNatural Orifice Endoscopic SurgeryAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeAchalasiaBifurcate peroral endoscopic myotomyEckardt scoreEpiphrenic esophageal diverticulum

Identifiers

PMID42380627

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.