ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026
Association of multidisciplinary team management with survival in sinonasal malignancies: a real-world IPTW cohort study.
Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
purposeSinonasal malignancies (SNMs) are rare, heterogeneous, and aggressive. High-quality evidence to guide management is limited, and the prognostic value of multidisciplinary team (MDT) management remains incompletely characterized. This study aims at evaluating the association of MDT management with survival outcomes and treatment selection among patients with SNMs.
methodsRetrospective cohort study including 304 consecutive patients with histologically confirmed SNMs treated at the First Affiliated Hospital of Sun Yat-sen University between September 2017 and December 2023. Patients were classified according to whether their cases underwent a formal MDT review process before the definitive treatment plan was initiated. The primary outcome was overall survival (OS). Baseline differences were addressed using stabilized inverse probability of treatment weighting (IPTW). Survival was analyzed with Kaplan-Meier estimates and weighted Cox proportional hazards models. Treatment patterns were compared using weighted logistic regression. Secondary outcomes included length of hospital stay and hospitalization costs.
resultsOf 304 included patients, 106 (34.9%) received MDT management. After weighting, 3-year and 5-year OS rates were 85.9% and 75.8% with MDT versus 74.8% and 63.3% without MDT (P = 0.034 and 0.125 respectively). MDT management was associated with longer OS (hazard ratio, 0.52; 95% CI, 0.30-0.91; P = 0.020). Subgroup analyses suggested consistent associations across all predefined subgroups. MDT involvement was also associated with shorter hospital stay without increased hospitalization costs.
conclusionsIn this single-center cohort, MDT management was associated with optimized treatment selection and improved overall survival in patients with SNMs, with consistent effects across clinical subgroups. Establishing efficient, standardized MDT workflows may help improve outcomes for sinonasal and skull base malignancies; prospective multicenter studies are warranted to validate these associations.
Indexed as
Identifiers
42380516What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.