Evidence map›Paper›PMID 42380286›Full record

ArticleExperimental & molecular medicine2026

Therapeutic effect of intranasal nicotinamide adenine dinucleotide in the restoration of olfactory dysfunction.

Shin Hyuk Yoo, Jung Yeon Jang, Jun-Sang Bae, Reiza Ventura, Eun Hee Kim, A Young Kim, Ji-Hun Mo, Jaewoo Park, Kyuho Kang, Yeogyun Yun and 4 more

Abstract read
In one paragraph

Article in Experimental & molecular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Shin Hyuk YooDepartment of Otorhinolaryngology, Dankook University College of Medicine, Cheonan, Republic of Korea.
Jung Yeon JangDepartment of Otorhinolaryngology - Head and Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Jun-Sang BaeDepartment of Otorhinolaryngology, Dankook University College of Medicine, Cheonan, Republic of Korea.
Reiza VenturaDepartment of Otorhinolaryngology, Dankook University College of Medicine, Cheonan, Republic of Korea.
Eun Hee KimDepartment of Otorhinolaryngology, Dankook University College of Medicine, Cheonan, Republic of Korea.
A Young KimDepartment of Otorhinolaryngology, Dankook University College of Medicine, Cheonan, Republic of Korea.
Ji-Hun MoDepartment of Otorhinolaryngology, Dankook University College of Medicine, Cheonan, Republic of Korea.
Jaewoo ParkDepartment of Biological Sciences and Biotechnology, Chungbuk National University, Cheongju, Republic of Korea.
Kyuho KangDepartment of Biological Sciences and Biotechnology, Chungbuk National University, Cheongju, Republic of Korea.ORCID http://orcid.org/0000-0003-3448-5336
Yeogyun YunInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, Republic of Korea.
Jun Hee LeeInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, Republic of Korea.
Yong-Jae KimInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, Republic of Korea.
Dong-Joon LeeInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, Republic of Korea.ORCID http://orcid.org/0000-0001-6532-9729
Ji Heui KimDepartment of Otorhinolaryngology - Head and Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. jhkim0217@amc.seoul.kr.ORCID http://orcid.org/0000-0002-9215-6867

Funding

Korea Health Industry Development Institute (KHIDI) RS-2025-25460239National Research Foundation of Korea (NRF) RS-2022-NR069663National Research Foundation of Korea (NRF) RS-2023-00220408
6 · The paper itself

Abstract

Olfactory dysfunction is a debilitating condition with no established treatment. This study evaluated the efficacy of intranasal (i.n.) NAD administration in restoring olfactory function. Cultured human olfactory stem cells (hOSCs) were treated with NAD and assessed by immunofluorescence staining, PCR, and western blot analyses. In vivo, mice with ZnSO

Indexed as

NADOlfaction DisordersAdministration, IntranasalAnimalsCell DifferentiationCells, CulturedDisease Models, AnimalHumansMaleMiceOlfactory MucosaOlfactory Receptor NeuronsNAD

Identifiers

PMID42380286
PMCPMC13434466

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.