Evidence map›Paper›PMID 42379827›Full record

ArticleMicrobiology spectrum2026

Comparative evaluation of EUCAST RAST and QuickMIC for rapid antimicrobial susceptibility testing of carbapenem-resistant organisms directly from positive blood cultures.

Nicole Degel-Brossmann, Tom Kimkes, Lucas Reibenspies, Jiabin Huang, Harald Seifert, Paul Higgins, Martin Christner, Martin Aepfelbacher, Cecilia Johansson, Christer Malmberg and 2 more

Abstract readComparative StudyEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nicole Degel-BrossmannInstitute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Hamburg, Germany.
Tom KimkesGradientech AB, Uppsala, Sweden.
Lucas ReibenspiesGradientech AB, Uppsala, Sweden.
Jiabin HuangInstitute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Hamburg, Germany.
Harald SeifertInstitute for Medical Microbiology, Immunology and Hygiene, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.ORCID 0000-0002-7732-4762
Paul HigginsInstitute for Medical Microbiology, Immunology and Hygiene, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Martin ChristnerInstitute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Hamburg, Germany.
Martin AepfelbacherInstitute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Hamburg, Germany.
Cecilia JohanssonGradientech AB, Uppsala, Sweden.ORCID 0000-0001-5965-2853
Christer MalmbergGradientech AB, Uppsala, Sweden.ORCID 0000-0003-3187-8732
Holger Rohde *Institute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Hamburg, Germany.ORCID 0000-0001-8587-4433
Benjamin Berinson *Institute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Hamburg, Germany.ORCID 0000-0003-2749-1201

Funding

Gradientech
6 · The paper itself

Abstract

Rapid availability of phenotypic susceptibility results is crucial for the timely detection of multidrug-resistant Gram-negative organisms. Several novel methods have been introduced that enable direct antimicrobial susceptibility testing (AST) from positive blood cultures. This study aimed to assess the analytical performance of the agar diffusion-based EUCAST rapid AST (RAST) method and the automated QuickMIC system using a challenging collection of highly resistant Gram-negative organisms. One hundred one Gram-negative bacteria (

Indexed as

Anti-Bacterial AgentsCarbapenemsGram-Negative BacteriaGram-Negative Bacterial InfectionsAcinetobacter baumanniiBlood CultureHumansKlebsiella pneumoniaeMicrobial Sensitivity TestsPseudomonas aeruginosaAnti-Bacterial AgentsCarbapenemsblood culturecomparative performance evaluationdiagnosticsEUCAST RASTQuickMICrapid ASTresistancesepsis

Identifiers

PMID42379827
PMCPMC13435937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.