ArticleIn vivo (Athens, Greece)
The Clinical Impact of Postoperative Complications After Gastric Cancer Surgery for the Clinical Course of Adjuvant Treatment and Survival.
Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
BACKGROUND/
aimThis study investigated whether postoperative complications (POCs) have a direct negative impact on survival or indirectly worsen survival outcomes by impairing the administration of adjuvant chemotherapy in patients with stage II/III gastric cancer (GC). PATIENTS AND
methodsPatients were retrospectively selected from the database of the Department of Gastric Surgery at the Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital (Tokyo, Japan). POCs were defined as postoperative complications of Clavien-Dindo grade II-V. Patients were categorized into two groups: those with POCs (C group) and those without POCs (NC group).
resultsA total of 465 patients were included in this study, and POCs occurred in 134 patients (28.8%). The 3- and 5-year overall survival (OS) rates were 71.0% and 59.5% in the C group, and 77.7% and 71.2% in the NC group, respectively. The differences between the two groups were statistically significant (
conclusionPOCs were associated with poorer survival and adversely affected the administration of adjuvant chemotherapy after gastric cancer surgery. These findings suggest that POCs not only have a direct negative impact on survival but also indirectly worsen prognosis by compromising the delivery of postoperative adjuvant chemotherapy.
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