ArticleIn vivo (Athens, Greece)
Development of a Plasma Spot Assay for Detection of Fluorophore-labeled Antibodies in Mouse Imaging Studies.
Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND/
aimMATERIALS AND
methodsWe developed a fluorescent plasma spot assay (FPSA) to measure relative Ab-F fluorescence in plasma and enable standardization of tissue fluorescence obtained during optical imaging studies.
resultsFPSA measurements were consistent with Ab-F concentration and degree-of-labeling data generated by conventional analytical methods, including immunoassay and spectrophotometry. Additionally, the FPSA was used to determine fluorophore type and DOL conditions with minimal effects on Ab-F clearance and tissue retention to minimize in-study artifacts.
conclusionThe FPSA can be performed concurrently with
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