ArticleBMJ open2026
Routine external aortic compression versus no aortic compression in elective caesarean delivery to reduce blood loss: study protocol of a randomised controlled trial.
Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05312658 (Aortic Compression Trial - a Randomized Controlled Trial to Reduce Blood Loss at Cesarean Section), which is not on this map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Aortic Compression Trial - a Randomized Controlled Trial to Reduce Blood Loss at Cesarean Section (ACT)
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionExternal aortic compression is used to reduce excessive blood loss in childbirth. However, it has never been evaluated for the prevention of postpartum haemorrhage. This study aims to investigate whether routine external aortic compression, in patients undergoing elective caesarean delivery, is an effective and acceptable preventive method to reduce severe postpartum haemorrhage. METHODS AND ANALYSIS: This multicentre, randomised, controlled, open-label trial aims to enrol 2246 patients across 10 maternity hospitals in Sweden. Patients with a live single or multiple pregnancy after 34 complete gestational weeks undergoing elective caesarean delivery will be randomised to either routine manual external aortic compression or no aortic compression (standard care). The primary objective is to investigate whether external aortic compression in caesarean delivery is an effective preventive method to reduce severe postpartum haemorrhage, defined as a calculated blood loss >1000 mL or blood transfusion within 48 hours. The secondary objectives are to investigate whether it reduces overall maternal morbidity, shortens time in surgery or hospital, affects patient-reported outcomes and is safe and acceptable to patients. Analyses will follow the intention-to-treat (ITT) principle, using generalised linear mixed-effects models for the primary and secondary outcomes with adjustment for study centre. Multiplicity for confirmatory outcomes will be controlled using a hierarchical testing procedure. ETHICS AND DISSEMINATION: Ethical approval was obtained on 20 September 2022 from the Swedish Ethical Review Authority (2022-04327-01), and amendments were approved on 28 November 2022 (2022-06377-02), 17 February 2025 (2025-00700-02) and 9 June 2026 (2026-03503-02). Results of the study will be published in peer-reviewed medical journals, presented at scientific meetings and communicated to the public through mass media. TRIAL REGISTRATION NUMBER: NCT05312658.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.