Evidence map›Paper›PMID 42378727›Full record

ArticleUltrasonics sonochemistry2026

Novel biosurfactant-stabilized nanoemulsions integrating interfacial stabilization and antibacterial activity for safe surface disinfection.

Geum-Jae Jeong, Hyo-Jin Kim, Ye-Hyeon Jo, Se-Chang Kim, Dong-Joo Park, Kyung-Jin Cho, Na-Yeon Kim, Jung-Min Lee, Minji Kim, Won-Kyo Jung and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ultrasonics sonochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Geum-Jae JeongDepartment of Food Science and Technology, Pukyong National University, Busan 48513, the Republic of Korea; Marine Integrated Biomedical Technology Center, The National Key Research Institutes in Universities, Pukyong National University, Busan 48513, the Republic of Korea; Research Center for Marine Integrated Bionics Technology, Pukyong National University, Busan 48513, the Republic of Korea.
Hyo-Jin KimMarine Integrated Biomedical Technology Center, The National Key Research Institutes in Universities, Pukyong National University, Busan 48513, the Republic of Korea; Interdisciplinary Program of Blue Food, Pukyong National University, Busan 48513, the Republic of Korea.
Ye-Hyeon JoMarine Integrated Biomedical Technology Center, The National Key Research Institutes in Universities, Pukyong National University, Busan 48513, the Republic of Korea; Interdisciplinary Program of Blue Food, Pukyong National University, Busan 48513, the Republic of Korea.
Se-Chang KimNational Marine Biodiversity of Korea, Seochun 33662, the Republic of Korea.
Dong-Joo ParkMarine Integrated Biomedical Technology Center, The National Key Research Institutes in Universities, Pukyong National University, Busan 48513, the Republic of Korea; Major of Biomedical Engineering, Division of Smart Healthcare, College of Information Technology and Convergence and New-senior Healthcare Innovation Center (BK21 Plus), Pukyong National University, Busan 48513, the Republic of Korea.
Kyung-Jin ChoKorea Food Research Institute, Wanju 55365, the Republic of Korea.
Na-Yeon KimMarine Integrated Biomedical Technology Center, The National Key Research Institutes in Universities, Pukyong National University, Busan 48513, the Republic of Korea; Interdisciplinary Program of Blue Food, Pukyong National University, Busan 48513, the Republic of Korea.
Jung-Min LeeMarine Integrated Biomedical Technology Center, The National Key Research Institutes in Universities, Pukyong National University, Busan 48513, the Republic of Korea; Interdisciplinary Program of Blue Food, Pukyong National University, Busan 48513, the Republic of Korea.
Minji KimMarine Integrated Biomedical Technology Center, The National Key Research Institutes in Universities, Pukyong National University, Busan 48513, the Republic of Korea; Research Center for Marine Integrated Bionics Technology, Pukyong National University, Busan 48513, the Republic of Korea.
Won-Kyo JungMarine Integrated Biomedical Technology Center, The National Key Research Institutes in Universities, Pukyong National University, Busan 48513, the Republic of Korea; Research Center for Marine Integrated Bionics Technology, Pukyong National University, Busan 48513, the Republic of Korea; Major of Biomedical Engineering, Division of Smart Healthcare, College of Information Technology and Convergence and New-senior Healthcare Innovation Center (BK21 Plus), Pukyong National University, Busan 48513, the Republic of Korea.
Young-Mog KimDepartment of Food Science and Technology, Pukyong National University, Busan 48513, the Republic of Korea; Marine Integrated Biomedical Technology Center, The National Key Research Institutes in Universities, Pukyong National University, Busan 48513, the Republic of Korea; Research Center for Marine Integrated Bionics Technology, Pukyong National University, Busan 48513, the Republic of Korea; Interdisciplinary Program of Blue Food, Pukyong National University, Busan 48513, the Republic of Korea. Electronic address: ymkim@pknu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemical disinfectants are widely used for microbial control. However, concerns regarding their safety and environmental impact have driven the development of alternative antimicrobial systems based on natural components. Here, a biosurfactant (BS) derived from Bacillus velezensis GJ1 was used to construct a natural grade nanoemulsion (NE) system using thyme oil as the oil phase. Unlike conventional formulations in which surfactants mainly act as passive stabilizers, BS in this system contributed to both interfacial stabilization and antibacterial activity, enabling the development of a natural-grade NE system with combined physicochemical and antibacterial functionalities. The resulting NEs exhibited stable physicochemical properties and consistent droplet characteristics. Antibacterial evaluation demonstrated strong activity against Listeria monocytogenes and Escherichia coli O157, with comparable efficacy across different co-surfactant systems. This suggests that BS may contribute to the antibacterial performance of the NE systems. Microscopic analyses confirmed the membrane disruption and increased permeability of the bacterial cells. Under contact surface conditions, the BS-containing NEs exhibited measurable antibacterial activity against both L. monocytogenes and E. coli O157 under the tested conditions. NEs exhibited low cytotoxicity, minimal skin irritation, and negligible phytotoxicity at antibacterial concentrations. The findings suggest the potential applicability of BS-stabilized NEs as natural antimicrobial systems in which the surfactant contributes to both interfacial stabilization and antibacterial activity. These results may provide useful insights for the development of effective and safer disinfectant formulations based on naturally derived components.

Indexed as

Anti-Bacterial AgentsBiosurfactantsDisinfectionNanostructuresSurface-Active AgentsBacillusEmulsionsEscherichia coli O157Listeria monocytogenesSurface PropertiesAnti-Bacterial AgentsEmulsionsSurface-Active AgentsAntibacterial activityBiosurfactantNanoemulsionNatural disinfectantSurface disinfection

Identifiers

PMID42378727
PMCPMC13330536

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.