ArticleLasers in surgery and medicine2026
Triggering of Koebner Phenomenon by Picosecond Laser in a Psoriatic Patient: Clinical and Immunopathologic Insights.
Article in Lasers in surgery and medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo report the first case of Koebner phenomenon induced by picosecond laser treatment in a patient with psoriasis. We analyzed the clinical and histopathological features and discussed the possible mechanism by which the laser's photomechanical effect triggered the reaction.
methodsA 58-year-old woman with well-controlled plaque psoriasis underwent 755-nm picosecond alexandrite laser treatment (pulse duration: 750 ps; fluence: 3.77 J/cm
resultsOne month after treatment, erythematous, scaly plaques emerged at the laser-irradiated sites. Clinical and dermoscopic findings were consistent with psoriasis. Histology confirmed psoriasiform changes, and immunohistochemistry demonstrated a T-cell-predominant infiltrate (CD3
conclusionsTo our knowledge, this is the first report of the Koebner phenomenon induced by picosecond laser therapy in a patient with psoriasis. Although picosecond lasers are known for minimal thermal damage, their photomechanical effects may activate immune responses and trigger new psoriatic lesions. Therefore, caution and careful monitoring are advised when using picosecond lasers in patients with psoriasis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.