Evidence map›Paper›PMID 42378536›Full record

ReviewThe journal of international advanced otology2025

Vestibular Migraine Revisited: A Narrative Review of Diagnostic Challenges and Treatment Strategies.

Petros Vlastarakos, Giorgos Sideris, Melina Kourklidou, Vasiliki Bousi, Efterpi Michailidou, Thomas Nikolopoulos

Abstract readReview
In one paragraph

Review in The journal of international advanced otology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Petros VlastarakosDepartment of 2nd Otolaryngology, National and Kapodistrian University of Athens School of Medicine, "Attikon" University Hospital, Athens, Greece.ORCID 0000-0002-2803-1971
Giorgos SiderisDepartment of 2nd Otolaryngology, National and Kapodistrian University of Athens School of Medicine, "Attikon" University Hospital, Athens, Greece.ORCID 0000-0002-5748-091X
Melina KourklidouDepartment of 2nd Otolaryngology, National and Kapodistrian University of Athens School of Medicine, "Attikon" University Hospital, Athens, Greece.ORCID 0009-0007-7695-423X
Vasiliki BousiDepartment of 2nd Otolaryngology, National and Kapodistrian University of Athens School of Medicine, "Attikon" University Hospital, Athens, Greece.ORCID 0000-0003-2695-3777
Efterpi MichailidouDepartment of Otorhinolaryngology, Head and Neck Surgery, Inselspital, University Hospital Bern, Bern, Switzerland.ORCID 0000-0003-1875-0937
Thomas NikolopoulosDepartment of 2nd Otolaryngology, National and Kapodistrian University of Athens School of Medicine, "Attikon" University Hospital, Athens, Greece.ORCID 0000-0001-5290-1810

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledVestibular migraine (VM) is a common yet frequently underdiagnosed neurological condition, marked by recurrent episodes of vertigo and other vestibular symptoms in association with migraine features. It predominantly affects women aged 30-50 years and has an estimated prevalence of 1%-5% in the general population. This narrative review explores current knowledge surrounding VM, including its epidemiology, proposed mechanisms, diagnostic complexities, and treatment approaches. The pathophysiology remains incompletely understood but may involve dysfunction in vestibule-cerebellar pathways, ion channel abnormalities, and trigeminal system activation. Diagnosing VM is clinically driven, requiring careful evaluation of vestibular complaints alongside migraine-associated symptoms. Patients commonly report vertigo and headaches, while clinical assessment may uncover ocular motor disturbances, canal paresis, and balance issues. Supplementary tests such as ocular and cervical vestibular evoked myogenic potentials can aid in diagnosis, though they are not definitive. Differential diagnosis is essential due to symptom overlap with other vestibular disorders like Ménière's disease, episodic ataxia type 2, and benign paroxysmal positional vertigo. Treatment includes acute interventions with vestibular suppressants and triptans, vestibular rehabilitation programs, and preventive pharmacotherapy such as β-blockers, calcium channel blockers, and certain antidepressants. Despite these options, clinical evidence remains scarce, primarily relying on small-scale trials and expert consensus. No universally effective regimen has yet been identified. Overall, VM poses significant diagnostic and therapeutic challenges, underscoring the need for further research to clarify its mechanisms, improve diagnostic precision, and develop evidence-based treatment strategies that could lessen its burden and improve patient outcomes.

Indexed as

Migraine DisordersVestibular DiseasesVestibular MigraineAdultCalcium Channel BlockersDiagnosis, DifferentialFemaleHumansMiddle AgedPrevalenceVertigoVestibular Evoked Myogenic PotentialsCalcium Channel BlockersMigraine-associated vertigopathophysiologyprophylaxistreatmentvestibular migraine

Identifiers

PMID42378536
PMCPMC12520148

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.