Evidence map›Paper›PMID 42377890›Full record

ArticlePain and therapy2026

Durable Outcomes and Intervention Avoidance in Low Back Pain Up to 5 Years After Percutaneous 60-Day Peripheral Nerve Stimulation.

Samir J Sheth, Denise D Lester, Jaudat Mahmood, Sarah E Trampota, G Lawson Smith, Raheleh Rahimi Darabad, Brandon D Swan, Meredith J McGee, Joseph W Boggs

Abstract read
In one paragraph

Article in Pain and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Samir J ShethSutter Health Systems, 7 Medical Plaza Drive, Suite 250, Roseville, CA, 95661, USA. samir.sheth@sutterhealth.org.
Denise D LesterCentral Virginia VA Health Care System, Richmond, VA, USA.ORCID http://orcid.org/0009-0003-3074-6057
Jaudat MahmoodShannon Medical Center, San Angelo, TX, USA.
Sarah E TrampotaAdvantage Pain Management, San Antonio, TX, USA.
G Lawson SmithUniversity of Arkansas for Medical Sciences, Little Rock, AR, USA.ORCID http://orcid.org/0000-0002-4595-9149
Raheleh Rahimi DarabadIndiana University Health, Indianapolis, IN, USA.ORCID http://orcid.org/0009-0006-0561-6535
Brandon D SwanSPR, Cleveland, OH, USA.ORCID http://orcid.org/0000-0001-5960-6822
Meredith J McGeeSPR, Cleveland, OH, USA.ORCID http://orcid.org/0000-0003-0823-3362
Joseph W BoggsSPR, Cleveland, OH, USA.ORCID http://orcid.org/0000-0002-7973-7990

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLow back pain (LBP) is a leading cause of disability worldwide, and treatment often necessitates invasive interventions that carry significant risks and economic burdens. While prior studies demonstrated durable benefit following percutaneous 60-day peripheral nerve stimulation (PNS), real-world data are needed to characterize long-term outcomes across routine clinical practice. This survey evaluated the durability of patient-reported improvements among a real-world cohort of patients with LBP who responded to 60-day PNS.

methodsA cross-sectional follow-up survey was administered to patients who previously responded to 60-day PNS targeting the lumbar medial branch nerves. Outcomes assessed included patient-reported percent pain relief and impression of change in quality of life (QoL), physical function, mood, and sleep. Participants also reported use or avoidance of other LBP treatments or interventions since completing 60-day PNS.

resultsThe survey was completed by 602 participants, with follow-up durations ranging from 6 to 68 months. Overall, 79% (475/602) of participants required no radiofrequency ablation (RFA), permanent implant, or surgery following 60-day PNS. Among participants who avoided subsequent interventions, 79% (376/475) reported durable improvements in at least one domain (≥ 50% pain relief and/or clinically meaningful improvement of QoL, physical function, mood, and/or sleep) at follow-up. Among participants without a prior permanent neurostimulator implant, 92% (309/336) of those who sought to avoid permanent implantation succeeded. Among those without prior low back surgery who wanted to avoid it, 95% (353/370) avoided surgery through follow‑up.

conclusionsThese findings suggest that patients with LBP who respond to percutaneous 60-day PNS may experience durable relief, with benefits sustained by some for 5+ years. Participants reported reductions in pain leading to improvements in other health domains, and avoidance of subsequent interventions, including surgery, permanent implants, and/or RFA, through long-term follow-up, highlighting the potential use of percutaneous 60-day PNS as a minimally invasive, short-term treatment capable of producing long-lasting benefits in patients with LBP.

Indexed as

Chronic low back painChronic painNeuromodulationPercutaneous peripheral nerve stimulationPeripheral nerve stimulation

Identifiers

PMID42377890
PMCPMC13623810

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.