Evidence map›Paper›PMID 42377530›Full record

SynthesisSurgical endoscopy2026

Safety and feasibility of same-day discharge after peroral endoscopic myotomy in esophageal motility disorders: a systematic review and meta-analysis.

Aamir Saeed, Umar Hayat, Tessa Herman, Samuel Igbinedion, Leonard Baidoo, Maham Hayat, Faisal Kamal, Sultan Mahmood, Mansour A Parsi, Mohammad Bilal and 1 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aamir SaeedDivision of Gastroenterology and Hepatology, University of Tennessee Health Sciences Center, 920 Madison Avenue, Memphis, TN, 38163, USA. aamirsaeed4444@gmail.com.ORCID http://orcid.org/0000-0001-8752-4867
Umar HayatDivision of Gastroenterology, Geisinger Wyoming Valley Medical Center, Wilkes-Barre, PA, USA.
Tessa HermanDivision of Gastroenterology, Vanderbilt University Medical Center, Nashville, TN, USA.
Samuel IgbinedionDivision of Gastroenterology and Hepatology, University of Tennessee Health Sciences Center, Chattanooga, TN, USA.
Leonard BaidooDivision of Gastroenterology and Hepatology, University of Tennessee Health Sciences Center, 920 Madison Avenue, Memphis, TN, 38163, USA.
Maham HayatCenter for Interventional Endoscopy, AdventHealth Orlando, Orlando, FL, USA.
Faisal KamalDivision of Gastroenterology, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Sultan MahmoodDivision of Gastroenterology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Mansour A ParsiDivision of Gastroenterology and Hepatology, University of Tennessee Health Sciences Center, 920 Madison Avenue, Memphis, TN, 38163, USA.
Mohammad BilalDivision of Gastroenterology and Hepatology, University of Colorado Anschutz, Anschutz, CO, USA.
Mark RadlinskiDivision of Gastroenterology, Vanderbilt University Medical Center, Nashville, TN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsPeroral endoscopic myotomy (POEM) is an effective treatment for esophageal motility disorders. There is limited data regarding the safety and feasibility of same-day discharge after POEM, and postoperative care lacks standardization. This study aims to assess the data on readmission rate, emergency department (ED) visits, and adverse events between same-day discharge (SDD) and admitted patients after POEM.

methodsSeveral databases were reviewed from inception to October 12, 2025. Outcomes of interest were readmissions, emergency department (ED) visits, adverse events, and post-procedural pain. Data were analyzed using a random-effect model.

resultsSeven retrospective studies with a total of 637 patients (384 SDD, 253 admitted) were included in the final analysis. There was no significant difference in 30-day readmission rate, OR (95% CI): 0.72 (0.26, 1.98), and ED visits, OR (95% CI): 1.04 (0.40, 2.70) between the SDD and the admitted groups. Pooled rates (95% CI) for overall adverse events were 19.4% (7.6%, 41.3%), and among these, the pooled rates (95% CI) for intraoperative adverse events were 10.4% (6.6%, 16.2%).

conclusionsIn conclusion, the findings of this systematic review and meta-analysis indicate that same-day discharge after POEM is a viable management strategy in carefully selected patients and highlight opportunities to refine postoperative care protocols. Further prospective studies will be essential to validate these results and to better define standardized criteria for safe same-day discharge of patients undergoing the POEM procedure.

Indexed as

Ambulatory Surgical ProceduresEsophageal Motility DisordersMyotomyNatural Orifice Endoscopic SurgeryPatient DischargeEmergency Room VisitsEmergency Service, HospitalFeasibility StudiesHumansPatient ReadmissionPostoperative ComplicationsAchalasiaEsophageal motility disordersPeroral endoscopic myotomyReadmissionsSame-day discharge

Identifiers

PMID42377530

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.