Evidence map›Paper›PMID 42377515›Full record

SynthesisSurgical endoscopy2026

Minimally invasive repair of iatrogenic bile duct injuries: a systematic review and meta-analysis.

Marios Alogakos, Ahmed Ghani, Abdullah R Ayesh, May Y Hajeir, Lamees M Al Darwashi, Christian A Than, Hayato Nakanishi, Benjamin E Johnson, Alexandra M Roch, Eugene P Ceppa

Erratum issuedAbstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Marios AlogakosDepartment of Surgery, Division of Surgical Oncology, Indiana University School of Medicine, 545 Barnhill Drive, EH 541, Indianapolis, IN, 46202, USA.
Ahmed GhaniSchool of Medicine, University College Dublin, Dublin, D04 C1P1, Ireland.
Abdullah R AyeshSchool of Medicine, University of Nicosia, 2417, Nicosia, Cyprus.
May Y HajeirSchool of Medicine, University of Nicosia, 2417, Nicosia, Cyprus.
Lamees M Al DarwashiSchool of Medicine, University of Nicosia, 2417, Nicosia, Cyprus.
Christian A ThanCambridge University Hospitals NHS Foundation Trust, Addenbrookes Hospital, Cambridge, CB2 0QQ, UK.
Hayato NakanishiDepartment of Surgery, Mayo Clinic, Rochester, MN, 55905, USA.
Benjamin E JohnsonDepartment of Surgery, Endeavor Health, Chicago, IL, 60625, USA.
Alexandra M RochDepartment of Surgery, Division of Surgical Oncology, Indiana University School of Medicine, 545 Barnhill Drive, EH 541, Indianapolis, IN, 46202, USA.
Eugene P CeppaDepartment of Surgery, Division of Surgical Oncology, Indiana University School of Medicine, 545 Barnhill Drive, EH 541, Indianapolis, IN, 46202, USA. eceppa@iu.edu.ORCID http://orcid.org/0000-0002-8368-2232

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBile duct injuries (BDI) are a rare but serious complication of cholecystectomy, associated with substantial morbidity and clinical burden. However, no consensus has been reached on the optimal surgical approach for the management of BDI. This meta-analysis aims to evaluate the safety and efficacy of minimally invasive surgery (MIS) for the repair of iatrogenic BDI.

methodsCochrane, CINAHL, Ovid Embase and Medline were searched from their inception date to March 2025. The Preferred Reporting Items for Systematic Reviews and Meta-Analysis reporting guidelines were followed. The review was registered prospectively on PROSPERO (CRD420251009530).

resultsA total of 246 patients with MIS for BDI repair from sixteen studies were included in the analysis. The pooled mean operative time was 219 min (95% CI: 183-255), and the pooled mean hospital stay was 6.5 days (95% CI: 5.2-7.8). The pooled mean estimated blood loss was 122 mL (95% CI: 84-160). The overall postoperative morbidity was 16.2% (95% CI: 0.092-0.233, I

conclusionsMIS appears safe and effective for the repair of iatrogenic BDIs and is associated with acceptable morbidity and low reoperation rate. However, given the lack of high-level evidence, further studies are needed to ascertain these findings.

Indexed as

Bile DuctsCholecystectomy, LaparoscopicIntraoperative ComplicationsMinimally Invasive Surgical ProceduresHumansIatrogenic DiseaseLength of StayOperative TimePostoperative ComplicationsBile duct injuryLaparoscopicMeta-analysisMinimally invasiveRoboticSurgery

Identifiers

PMID42377515
PMCPMC13161001

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.