Evidence map›Paper›PMID 42377474›Full record

SynthesisSurgical endoscopy2026

GERD remission and safety profile of Single Anastomosis Sleeve Ileal (SASI) bypass vs sleeve gastrectomy (SG): a systematic review and meta-analysis.

Josélio Rodrigues de Oliveira Filho, Pedro Bicudo Bregion, Rafaela Hamada Juca, Giulia Almiron da Rocha Soares, Ghadeer Naji Shnawa, Nari Sabeti, Victor Kenzo Ivano, Cornelia L Griggs

Abstract readMeta-AnalysisSystematic ReviewComparative Study
PubMed Publisher
In one paragraph

Synthesis in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Josélio Rodrigues de Oliveira FilhoDepartment of Pediatric Surgery, Massachusetts General Hospital, Boston, MA, 02114, USA.ORCID http://orcid.org/0000-0001-9061-2948
Pedro Bicudo BregionState University of Campinas, Campinas, Brazil.
Rafaela Hamada JucaState University of Campinas, Campinas, Brazil.
Giulia Almiron da Rocha SoaresSantos Metropolitan University, Santos, Brazil.
Ghadeer Naji ShnawaDepartment of Pediatric Surgery, Massachusetts General Hospital, Boston, MA, 02114, USA.
Nari SabetiDepartment of Surgery, Massachusetts General Hospital, Boston, MA, USA.
Victor Kenzo Ivano *State University of Campinas, Campinas, Brazil.
Cornelia L Griggs *Department of Pediatric Surgery, Massachusetts General Hospital, Boston, MA, 02114, USA. cgriggs@mgb.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSleeve gastrectomy (SG) is widely recognized for its association with gastroesophageal reflux disease (GERD) and reduced sustained weight loss in the long term. The Single Anastomosis Sleeve Ileal (SASI) bypass was introduced as an alternative to enhance the metabolic benefits of SG, improve GERD outcomes, address nutritional challenges of ileal bypasses, and maintain duodenal access.

methodsThis study is a systematic review and meta-analysis of the comparative safety and efficacy of SASI bypass vs SG. A literature search in PubMed, Scopus, Embase, and Cochrane identified 234 articles after duplicate removal. Primary outcomes were GERD remission and complication rates over the follow-up period of each study including all complications reported by the authors, while secondary outcomes included weight loss and obesity-related condition remission.

resultsThirteen studies, including 2 RCTs and eleven observational studies, analyzed 960 SG and 396 SASI bypass patients. SASI bypass showed significantly higher GERD remission (OR 7.64; 95% CI [2.81; 20.78]; P < 0.001; I

conclusionSASI bypass offers superior GERD remission over SG but with potentially higher associated morbidity. Both techniques effectively promote weight loss and obesity-related condition remission, with SASI having a slight metabolic advantage due to intestinal bypass. Further research including prospective studies are needed to validate these findings and optimize postoperative care.

Indexed as

GastrectomyGastroesophageal RefluxIleumObesity, MorbidAnastomosis, SurgicalHumansPostoperative ComplicationsRemission InductionTreatment OutcomeWeight LossBariatric surgeryMeta-analysisObesity-related medical problemRemissionSingle Anastomosis Sleeve Ileal Bypass

Identifiers

PMID42377474

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.