Evidence map›Paper›PMID 42377158›Full record

ArticleLung India : official organ of Indian Chest Society2026

MAD vs. AHI: Sleep patterns, oxygenation among polysomnography diagnosed by OSA patients.

L B Pranav Varshan, Irfan Ismail Ayub, Sendilkumar Balasundaram

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Article in Lung India : official organ of Indian Chest Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

3 authors.

L B Pranav VarshanDepartment of Respiratory, School of Allied Health Sciences, VIMS Hospital Campus, Vinayaka Mission's Research Foundation (Deemed to be University), Salem, Tamil Nadu, India.
Irfan Ismail AyubDeparment of Pulmonology, Sri Ramachandra Institute of Higher Education and Research (Deemed to be University), Chennai, Tamil Nadu, India.
Sendilkumar BalasundaramDepartment of Public Health, School of Allied Health Science, Vinayaka Missions Research Foundation, Deemed to be University, Salem, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveObstructive sleep apnea is a common sleep disorder characterized by repeated airway obstructive during sleep, leading to breating pauses, reduced sleep quality and decreased blood oxygen levels. MATERIALS AND

methodsPolysomnographic data in Obstructive Sleep Apnea patients were analysed to explore correlations between Apnea Hypopnea Index, Mean Apnea hypopnea Duration, oxygen desaturation and sleep stages.

resultsAmong 136 Obstructive Sleep Apnea patients, Mean Apnea hypopnea duration showed a mild correlation with Apnea Hypopnea Index but no association with age, weight and height. Patients with longer Mean Apnea hypopnea duration had association ( P < 0.05) with poorer oxygenation, lower average saturation, loss of sleep, Mean oxygen desaturation, shorter sleep latency, less Non Rapid Eye Movement 3, more Non Rapid Eye Movement 1 and higher arousal/desaturation. After adjusting Apnea Hypopnea Index, Mean Apnea hypopnea duration remained significantly associated with Epworth Sleep Scale, sleep latency, Non Rapid Eye Movement 1/3, arousal index and all oxygen metrics. These associations were stronger in severe Obstructive Sleep Apnea ( n = 90), while in mild-moderate cases ( n = 46), only Non Rapid Eye Movement 3 duration correlated negatively with Mean Apnea hypopnea duration ( r = -0.14, P = 0.02).

conclusionMean apnea hypopnea duration emerged as an independent marker of oxygen desaturation and sleep disruption in OSA, beyond the Apnea Hypopnea Index. Its critical relevance was more pronounced in severe cases suggesting added value in assessing disease burden. Incorporating event duration into routine evaluation may refine patient stratification and guide targeted management strategies.

Indexed as

Apnea hypopnea indexapnea indexmean apnea hypopnea durationobstructive sleep apneapolysomnography

Identifiers

PMID42377158
PMCPMC13367539

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