ArticleLung India : official organ of Indian Chest Society2026
Asthma, COPD, and asthma-COPD overlap: A comparative study of inflammatory biomarkers and quality of life.
Article in Lung India : official organ of Indian Chest Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAsthma, COPD, and ACO are chronic airway disorders with distinct and overlapping features. This study aimed to compare clinical profiles, inflammatory biomarkers, and quality of life among these groups.
methodsA cross-sectional study was conducted on 168 patients (56 each with asthma, COPD, and ACO). All participants underwent clinical assessment, spirometry, St George's Respiratory Questionnaire (SGRQ), skin prick testing, and measurement of inflammatory markers, including FeNO, eosinophil count, total IgE, vitamin D, hs-CRP, and interleukins (IL-4, 5, 6, 8, 13, 17, 33).
resultsACO patients were younger than COPD patients but older than asthma patients. Asthma patients had the highest prevalence of allergic rhinitis and skin prick positivity. FEV 1 and FEV 1 /FVC were significantly lower in COPD and ACO compared to asthma, but not different between COPD and ACO. Bronchodilator response was higher in asthma and ACO than in COPD. Asthma patients had significantly higher FeNO, eosinophil counts, and IgE levels compared to COPD, with ACO showing intermediate values. IL-4 and IL-5 were highest in asthma, IL-6 and IL-8 in COPD, with ACO again showing intermediate levels. ACO patients had the highest SGRQ scores, indicating the worst quality of life. Correlation analysis showed group-specific associations between interleukins and clinical parameters.
conclusionACO exhibits intermediate clinical and inflammatory profiles between asthma and COPD. While individual biomarkers assist in characterizing these diseases, a combination of clinical, functional, and inflammatory parameters offers better differentiation. ACO patients experience a significant symptom burden, necessitating tailored diagnostic and therapeutic approaches.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.