ReviewCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2026
Disparities in Rural-Urban Cancer Care Outcomes among Pediatric, Adolescent, and Young Adult Populations: A Comprehensive Narrative Review.
Review in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pediatric cancer survival has improved substantially in recent decades; however, these gains remain unevenly distributed across populations. The National Cancer Institute has identified persistent disparities in pediatric cancer as a critical research priority, underscoring the need for focused investigation. This comprehensive narrative review examines the multifactorial contributors to rural-urban inequities in pediatric and adolescent and young adult (AYA) oncology. An extensive literature search of PubMed, Web of Science, Scopus, and the Cochrane Library identified English-language studies with data spanning 1973 to 2025, assessing disparities in rural cancer care and outcomes among US children (ages 0-18 years) and AYAs (ages 15-39 years). Compared with urban patients, rurality and long-distance travel to cancer care were often associated with poorer continuity of care; increased financial toxicity; reduced access to clinical trials, advanced therapies, and specialists; inadequate survivorship and supportive care; increased morbidity; and inferior survival. Disparities were further amplified among racial and ethnic minorities, who experienced decreased overall survival and increased early mortality across multiple cancer types. This review provides the first comprehensive synthesis of structural, geographic, and social drivers of rural cancer disparities and highlights multidisciplinary, evidence-based strategies to improve equitable access and outcomes for children and AYAs living outside major urban centers.
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