Evidence map›Paper›PMID 42377030›Full record

ArticleJournal of virology2026

Oropouche virus causes acute hepatitis in mice controlled by type I interferons.

Cade E Sterling, Rachael E Rush, Jackson J McGaughey, Brooke A Snow, Alexandra J Benton, W Paul Duprex, Gaya K Amarasinghe, Satdarshan P Monga, Amy L Hartman

Abstract read
In one paragraph

Article in Journal of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Cade E SterlingCenter for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0009-0009-7294-9294
Rachael E RushCenter for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-7481-7134
Jackson J McGaugheyCenter for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Brooke A SnowCenter for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Alexandra J BentonCenter for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
W Paul DuprexCenter for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-1716-6376
Gaya K AmarasingheDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.ORCID 0000-0002-0418-9707
Satdarshan P MongaDepartment of Pharmacology, Department of Medicine, Pittsburgh Liver Research Center, Organ Pathobiology and Therapeutic Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-8437-3378
Amy L HartmanCenter for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-0857-2973

Funding

Vaccines and Therapeutic Antibodies to Respiro, Rubula, Peribunya and Phenuiviridae (R2P2)-ReVAMPPU19AI181984 · NIAID · WASHINGTON UNIVERSITY · PI MOSCONA, ANNE, RAPPUOLI, RINO · 2024 to 2024
$44.1M
Practices CoreUC7AI180311 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI William Paul Duprex · 2023 to 2026
$13.2M
Pittsburgh Liver Research CenterP30DK120531 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Satdarshan Singh Monga · 2019 to 2026
$10.9M
Viral Persistence and PathogenesisT32AI049820 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DELUCA, NEAL A. · 2001 to 2024
$5.5M
Characterizing the role of LDL related receptor 1 (Lrp1) as host entry factor for multiple bunyavirusesR01AI169850 · NIAID · WASHINGTON UNIVERSITY · PI Gaya K. Amarasinghe, Amy L Hartman · 2023 to 2026
$3.1M
Mechanisms of Neuronal Infection by Prototype Emerging BunyavirusesR01AI178378 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Amy L Hartman · 2023 to 2026
$3.0M
Discovery of Bunyaviral Endonuclease Inhibitors for Anti ViralR42AI165102 · NIAID · MICROBIOTIX, INC · PI Gaya K. Amarasinghe, Gai Liu · 2025 to 2026
$1.9M
Role of Myeloid Cell Lrp1 in Rift Valley Fever Virus Infection and DisseminationF32AI191453 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WATKINS, RACHAEL RUSH · 2025 to 2025
$86k
NIAID NIH HHS F32 AI191453NIAID NIH HHS R01 AI169850NIAID NIH HHS R01 AI178378NIAID NIH HHS R42 AI165102NIAID NIH HHS T32 AI049820NIAID NIH HHS U19 AI181984NIAID NIH HHS UC7 AI180311NIDDK NIH HHS P30 DK120531
6 · The paper itself

Abstract

Oropouche virus (OROV), a member of the

Indexed as

Bunyaviridae InfectionsHepatitis, Viral, AnimalInterferon Type IOrthobunyavirusAcute DiseaseAnimalsDisease Models, AnimalFemaleHumansLiverMiceReceptor, Interferon alpha-betaInterferon Type IReceptor, Interferon alpha-betabunyavirusmouse modeloropouche virusperibunyavirusviral hepatitis

Identifiers

PMID42377030
PMCPMC13386938

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.