ArticlePolish journal of microbiology2026
Longitudinal Changes in Selected Gut Microorganisms During Gluten-Free Diet in Pediatric Coeliac Disease.
Article in Polish journal of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Alterations in gut microbiota have been reported in coeliac disease (CeD). However, longitudinal evidence distinguishing disease-related effects from diet-driven changes after gluten-free diet initiation remains scarce, particularly in pediatric cohorts. The present study aimed to evaluate time-dependent changes in selected intestinal microorganisms in children with CeD before and during adherence to a gluten-free diet and to compare these findings with those of healthy controls. Microbial DNA isolates from stool samples of pediatric patients with CeD (n = 24) and healthy children (n = 24) were analyzed by quantitative real-time PCR. Samples from CeD patients were categorized into four time points: pre-diet, 6-month, 1-year, and 2-year follow-up. The healthy controls were assessed once. The prevalence and microbial load of selected microorganisms were evaluated.
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