Evidence map›Paper›PMID 42376897›Full record

ArticleGeriatrics & gerontology international2026

A High Geriatric Depression Scale Score on Admission to Hospital Predicts a Worse Clinical Frailty Scale Score After Discharge.

Yosuke Yamada, Hirotaka Nakashima, Masaaki Nagae, Kazuhisa Watanabe, Chisato Fujisawa, Hitoshi Komiya, Tomihiko Tajima, Shosuke Satake, Yasushi Takeya, Yumi Umeda-Kameyama and 1 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Geriatrics & gerontology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yosuke YamadaDepartment of Community Healthcare and Geriatrics, Graduate School of Medicine, Nagoya University, Nagoya, Japan.
Hirotaka NakashimaDepartment of Community Healthcare and Geriatrics, Graduate School of Medicine, Nagoya University, Nagoya, Japan.
Masaaki NagaeDepartment of Community Healthcare and Geriatrics, Graduate School of Medicine, Nagoya University, Nagoya, Japan.
Kazuhisa WatanabeDepartment of Community Healthcare and Geriatrics, Graduate School of Medicine, Nagoya University, Nagoya, Japan.
Chisato FujisawaDepartment of Community Healthcare and Geriatrics, Graduate School of Medicine, Nagoya University, Nagoya, Japan.ORCID https://orcid.org/0000-0002-0926-5000
Hitoshi KomiyaDepartment of Community Healthcare and Geriatrics, Graduate School of Medicine, Nagoya University, Nagoya, Japan.ORCID https://orcid.org/0000-0001-8037-3496
Tomihiko TajimaDepartment of Community Healthcare and Geriatrics, Graduate School of Medicine, Nagoya University, Nagoya, Japan.
Shosuke SatakeDepartment of Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Japan.ORCID https://orcid.org/0000-0003-0301-1461
Yasushi TakeyaDepartment of Evidence-Based Clinical Nursing, Division of Health Sciences, Graduate School of Medicine, Osaka University, Osaka, Japan.
Yumi Umeda-KameyamaDementia Center, The University of Tokyo Hospital, Tokyo, Japan.ORCID https://orcid.org/0000-0003-4353-3424
Hiroyuki UmegakiDepartment of Community Healthcare and Geriatrics, Graduate School of Medicine, Nagoya University, Nagoya, Japan.

Funding

Japan Society for the Promotion of Science (JSPS) JP21H02826
6 · The paper itself

Abstract

aimThis study aimed to determine whether a higher Geriatric Depression Scale-15 (GDS-15) score on admission is associated with worsening of the Clinical Frailty Scale (CFS) score from discharge to 3 months after discharge in older patients hospitalized for acute care.

methodsThis multicenter prospective study was performed at three university hospitals and one national medical center in Japan between October 2019 and July 2023. A total of 601 patients were analyzed. Post-discharge CFS worsening was defined as a ≥ 1-point increase in CFS score from discharge to 3 months after discharge. Logistic regression, subgroup, sensitivity, and formal interaction analyses were performed.

resultsFrom discharge to 3 months after discharge, the CFS score worsened in 87 patients (14.5%). The worsened group had significantly higher GDS-15 scores on admission (p = 0.047). After adjustment for age, sex, baseline CFS score, CCI value, and MMSE score, a higher GDS-15 score was associated with greater odds of CFS worsening (OR 1.109, p = 0.002). In subgroup analysis, this association was observed in patients with baseline CFS scores ≥ 4 (OR 1.106, p = 0.007), but not in those with baseline CFS scores ≤ 3. The formal interaction test was not significant (p = 0.969). The association remained significant in sensitivity analyses.

conclusionsA higher GDS-15 score on admission independently predicted post-discharge CFS worsening in older acute-care inpatients. GDS-15 screening on admission may help identify patients requiring closer post-discharge monitoring for frailty deterioration.

Indexed as

DepressionFrail ElderlyFrailtyGeriatric AssessmentPatient DischargeAgedAged, 80 and overFemaleHospitalizationHumansJapanMaleProspective Studiesacute hospitalizationclinical frailty scaledepressionfrailtypost‐discharge

Identifiers

PMID42376897
PMCPMC13316975

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