ArticleCell biology international2026
Adipose-Derived Stem Cells Differentiate Into Insulin-Producing Cells in 2D Culture With Photobiomodulation: A Comparative Analysis of Wavelength and Fluence Parameters.
Article in Cell biology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Diabetes mellitus is a chronic metabolic disorder characterized by the loss or dysfunction of insulin-producing beta (β) cells. Adipose-derived stem cells (ADSCs) represent a promising source for generating functional insulin-producing β cells due to their accessibility and differentiation potential. Photobiomodulation (PBM), a non-invasive light-based therapy, has emerged as an innovative strategy to enhance stem cell differentiation efficiency. Evidence suggests that green (525 nm) and near-infrared (825 nm) wavelengths, applied individually or in combination, can modulate cellular metabolism, ATP production, and differentiation-related signaling pathways, thereby influencing ADSC commitment toward insulin-producing β-cell-like phenotypes. This in vitro study evaluated the effects of PBM at 525 nm and 825 nm, delivered individually and in combination at energy fluences of 5 J/cm
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