ArticleOTO open
Patient-Reported Swallowing Outcomes ≥5 Years After Neoadjuvant Chemotherapy and Transoral Robotic Surgery for HPV-positive Oropharyngeal Carcinoma.
Article in OTO open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To evaluate long-term swallowing outcomes in patients with HPV-associated oropharyngeal squamous cell carcinoma (HPV + OPSCC) following neoadjuvant chemotherapy (NAC) and transoral robotic surgery (TORS) (NAC + S). Study Design: Retrospective cross-sectional study. Setting: Single academic institution. Methods: Patients completed the MD Anderson Dysphagia Inventory (MDADI) at various time points following the completion of treatment. Patients requiring adjuvant treatment, experiencing recurrent disease, or who did not complete an MDADI at least 5 years following treatment were excluded from the study. A linear regression model was explored to determine the relationship between time since treatment and MDADI score. Results: A total of 21 patients treated with the NAC + S protocol were included. The average time between treatment and the most recent follow-up was 101.5 months. 1 patient had a composite MDADI score indicating poor function (<60), 3 indicating adequate function (≥60 to <80), and 17 indicating optimal function (≥80). There was no significant change in overall MDADI score ( Conclusion: Patients who were successfully treated with NAC + S maintain their favorable swallowing outcomes on long-term follow-up. A small improvement in functional MDADI sub-score may represent compensatory strategies or rehabilitation over time.
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