Evidence map›Paper›PMID 42376526›Full record

ArticleOpen veterinary journal2025

Toxicity and potential of propolis resin to boost embryo growth of broilers.

Maslichah Mafruchati, Lailatul Fadliyah, Akhmad Kusuma Wardhana, Intan Idiana Hassan, Joni Susanto

Abstract read
In one paragraph

Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maslichah MafruchatiDepartment of Veterinary Anatomy, Faculty of Veterinary Medicine (60115), Universitas Airlangga, Mulyorejo, Surabaya, Indonesia.
Lailatul FadliyahFaculty of Vocational Studies, Airlangga University, Indonesia.
Akhmad Kusuma WardhanaDepartment of Environmental Management, Prince of Songkla University, Hatyai, Surabaya, Thailand.
Intan Idiana HassanSchool of Health Sciences, Universiti Sains Malaysia, George Town, Malaysia.
Joni SusantoFaculty of Medicine, Department of Anatomy, Histology, Universitas Airlangga Campus A, Surabaya, Indonesia.

Funding

LPPM of Universitas Airlangga, Indonesia
6 · The paper itself

Abstract

Background: Propolis resin could be used as a therapeutic agent for chicken embryos, but its toxicity must be evaluated before application in livestock. Aim: This study aimed to investigate the toxicity and growth-promoting properties of propolis resin on the embryo of the chicken. Methods: Fertilized broiler eggs were used as experimental samples by being injected with propolis resin. The solution volume was predetermined to be 1 ml per egg for each treatment dose. Results: The result showed that the morphology of chicken eggs was viable after propolis resin injection on days 13-21 after inoculation. Moreover, 62.5 mg/egg was the effective dose, 125 mg/egg was the Toxic dose 250 mg/egg was the lethal dose. A mid-range dose (62.5-125 mg/egg) was associated with higher embryo weight and wing bone length compared to controls, though differences require further confirmation. Conclusion: Propolis resin at intermediate concentration can boost embryonic growth, but higher doses rapidly induce toxicity. These findings emphasize the importance of dose optimization and chemical profiling before

Indexed as

ChickensEmbryonic DevelopmentPropolisAnimalsChick EmbryoDose-Response Relationship, DrugPropolisChicken embryoFood productionPropolis resinToxicity

Identifiers

PMID42376526
PMCPMC13314042

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.