Improvement in coat condition observed in dogs with suspected alopecia X through combined supplementation with nutrients for the coat and skin: A case report.

Background: Alopecia X is characterized by non-inflammatory hair loss and is commonly observed in dogs with double coats and dense undercoats. The exact cause of alopecia X remains unknown, and its complex etiology and diverse responses to treatment make it challenging for veterinarians to manage. Case Description: An 8-year-old Chihuahua (male, unneutered, weight 4.1 kg) with significant hair loss presented to our clinic. The owner declined to provide a definitive diagnosis; consequently, based on a physical examination and a series of questions, a diagnosis of suspected alopecia was made. Horse placenta extract, taurine, and vitamin B complex (B1, B2, B5, and B6) were administered as nonpharmacological therapies. Following a 66-day supplementation regimen, a marked improvement in hair coat coverage was observed, with the back, sides, and abdomen exhibiting near-full-coat coverage. No adverse events were observed during the supplementation period. Supplementation was terminated following an enhancement in coat condition, and no hair loss was observed during a 76-week follow-up period. Conclusion: The combination of supplements from different categories may be a novel treatment option for owners who wish to pursue non-invasive treatment for alopecia in their dogs.