Evidence map›Paper›PMID 42376337›Full record

ArticleDigital journal of ophthalmology : DJO2025

Accuracy of an artificial intelligence chatbot in identifying congenital glaucoma from other ocular etiologies.

Nur Cardakli, Bo Wang, Jefferson J Doyle, Courtney L Kraus

Abstract read
In one paragraph

Article in Digital journal of ophthalmology : DJO, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nur CardakliWilmer Eye Institute, Johns Hopkins Hospital, Baltimore, Maryland.
Bo WangWilmer Eye Institute, Johns Hopkins Hospital, Baltimore, Maryland.
Jefferson J DoyleWilmer Eye Institute, Johns Hopkins Hospital, Baltimore, Maryland.
Courtney L KrausWilmer Eye Institute, Johns Hopkins Hospital, Baltimore, Maryland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate the accuracy and appropriateness of responses provided by ChatGPT in identifying congenital glaucoma from a series of written and image-based prompts. Methods: A series of questions regarding common signs and symptoms of congenital glaucoma were developed and queried to ChatGPT-3.5 and ChatGPT-4.0, and a set of publicly available images of patients with congenital glaucoma were queried to the image search function of ChatGPT-4.0. Outputs were graded by three pediatric ophthalmologists with expertise in congenital glaucoma. Completeness of response, accuracy, potential for harm, and concern for glaucoma were assessed by each reviewer. Results: A higher proportion of prompt responses from ChatGPT-4.0 were graded to be acceptable/appropriate than from ChatGPT-3.5 (22/33 vs 9/33 [ Conclusions: Despite superior performance from ChatGPT-4.0 compared with ChatGPT-3.5 in raising concern for congenital glaucoma and appropriateness of responses from text-based prompts, it performed poorly in recognizing clinical images of congenital glaucoma.

Indexed as

Artificial IntelligenceGlaucomaGenerative Artificial IntelligenceHumansReproducibility of Results

Identifiers

PMID42376337
PMCPMC13313138

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.