ArticleSaudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
Emerging diagnostic modalities in microbial keratitis: Beyond culture and smear.
Article in Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Microbial keratitis (MK) is a significant cause of corneal blindness worldwide, necessitating accurate and timely diagnosis for effective treatment. Traditional diagnostic techniques, such as corneal scraping for staining and culture, have limitations in sensitivity, specificity, and result time. This review analyzed peer-reviewed PubMed articles to explore emerging diagnostic modalities that address these challenges, focusing on molecular diagnostics, imaging techniques, and artificial intelligence (AI). Polymerase chain reaction and next-generation sequencing offer rapid and sensitive detection of the causative pathogen, although limitations include cost and false positives. Imaging technologies, such as
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