ArticleSaudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
A 5-year review of fungal keratitis in Oklahoma.
Article in Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo evaluate demographics, risk factors, clinical characteristics, and visual outcomes of fungal keratitis (FK) in Oklahoma over 5 years and identify factors linked to poor outcomes.
methodsA retrospective chart review was conducted at the Dean McGee Eye Institute (University of Oklahoma) from January 2019 to February 2024, identifying 103 cases of FK among 1213 corneal ulcer patients. Poor outcomes were defined as final best corrected visual acuity (BCVA) ≤20/70 or need for surgery. Statistical comparisons were performed using the Chi-square test, Wilcoxon rank-sum test, and multivariate logistic and linear regression analyses.
resultsOverall, 42/103 (40.8%) of patients had poor outcomes. Mold was the most common etiology (74.8%). Topical steroid use (odds ratio 3.57,
conclusionThe epidemiologic patterns observed in this geographic region of the United States, a mold-predominant environment with frequent steroid misuse and CL-associated disease, highlight the importance of early diagnosis, risk-factor modification, and ready access to adjunctive therapies. As FK incidence continues to rise in similar climates, these lessons from our regional cohort may help refine triage pathways and inform treatment approaches to reduce preventable vision loss.
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