ArticleSaudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
Effect of ultraviolet-A-induced corneal collagen cross-linking in the management of
Article in Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeBacterial keratitis remains a significant cause of corneal morbidity and visual impairment. Increasing resistance to antimicrobial therapy has prompted interest in alternative or adjunctive treatments, including corneal collagen cross-linking (CXL) with ultraviolet-A (UV-A) and riboflavin. The aim of the study is to develop an
methodsThree human donor corneas were dissected into quadrants and assigned to four experimental groups: (1) control (noninoculated and nontreated), (2) inoculated only, (3) inoculated and postinfection cross-linked, and (4) precross-linked and subsequently inoculated. All infected samples were exposed to
resultsThe postinfection CXL group demonstrated a significant reduction in bacterial load compared to the inoculated-only and precross-linked groups. Moreover, there was limited bacterial spread, and posterior stromal architecture was better preserved in the treated corneas.
conclusionThe study successfully established a human
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.