Evidence map›Paper›PMID 42376088›Full record

ArticleOpen veterinary journal2026

Effects of probiotic formulations on gastrointestinal tract morphological changes and gut microbiota in Hu lambs.

Ting Xu, Siling Ding, Ye Xu, Siyu Yang, Yian Yao, Pengcheng Wan, Guoqing Shi, Yimin Wang, Feng Guan, Junfang Jiang

Abstract read
In one paragraph

Article in Open veterinary journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ting XuCollege of Life Sciences, China Jiliang University, Hangzhou, China.
Siling DingCollege of Life Sciences, China Jiliang University, Hangzhou, China.
Ye XuCollege of Life Sciences, China Jiliang University, Hangzhou, China.
Siyu YangCollege of Life Sciences, China Jiliang University, Hangzhou, China.
Yian YaoCollege of Life Sciences, China Jiliang University, Hangzhou, China.
Pengcheng WanResearch Institute of Animal Husbandry and Veterinary, Xinjiang Agricultural Reclamation Academy, Shihezi, China.
Guoqing ShiResearch Institute of Animal Husbandry and Veterinary, Xinjiang Agricultural Reclamation Academy, Shihezi, China.
Yimin WangHangzhou Caiyang Animal Husbandry Co., Ltd, Hangzhou, China.
Feng GuanCollege of Life Sciences, China Jiliang University, Hangzhou, China.
Junfang JiangInstitute of Animal and Veterinary Science, Academy of Zhejiang Agriculture Science, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Gut microbiota plays an important role in the digestive system of ruminants, affecting the health status of Hu sheep and their development and production traits. Factors such as gender, age, diet, and probiotic formulations may influence their compositions. Aim: This study aimed to investigate the morphological changes in the gastrointestinal tract and gut microbiota dynamics during postnatal development of Hu lambs and evaluate the effects of probiotic supplementation. Methods: During the 60-day experiment, rumen, duodenum, jejunum, and ileum samples were collected at 2 hours, 20 days, and 55 days after birth. High-throughput 16S rRNA gene sequencing was employed to analyze microbial diversity, and morphological analysis was conducted to compare differences in the digestive tract surface tissues. Results: The results indicated that the length of the rumen papillae and the height of the villi in the jejunum and ileum continued to increase with increasing age. The overall diversity of the gut microbiota exhibited a gradual upward trend. The microbial diversity indices were higher in the experimental group than in the control group at corresponding time points ( Conclusion: Probiotic supplementation promotes early gastrointestinal tract development, enhances the colonization of beneficial bacteria, and improves microbial diversity in Hu lambs.

Indexed as

Gastrointestinal MicrobiomeGastrointestinal TractProbioticsSheep, DomesticAnimal FeedAnimalsDietFemaleMaleRNA, Ribosomal, 16SRumenSheepRNA, Ribosomal, 16S16S rRNA gene sequencingGIT morphologyGut microbiotaHu lambsProbiotic formulations

Identifiers

PMID42376088
PMCPMC13314136

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.