Evidence map›Paper›PMID 42376020›Full record

ArticleERJ open research2026

The epidemiological burden and societal cost of 14 respiratory conditions in the World Health Organization European region: systematic evidence map and economic analysis.

Sue Harnan, Matthew Franklin, Colin Angus, Joan B Soriano, Ane Johannessen, Anthea Sutton, Judith Garcia-Aymerich, Amy Auer, Christopher Carroll, Emma Simpson and 3 more

Abstract read
In one paragraph

Article in ERJ open research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sue HarnanSheffield Centre for Health and Related Research, The University of Sheffield, Sheffield, UK.
Matthew FranklinSheffield Centre for Health and Related Research, The University of Sheffield, Sheffield, UK.
Colin AngusSheffield Centre for Health and Related Research, The University of Sheffield, Sheffield, UK.
Joan B SorianoServicio de Neumología, Hospital Universitario de la Princesa, Madrid, Spain.ORCID https://orcid.org/0000-0001-9740-2994
Ane JohannessenDepartment of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Anthea SuttonSheffield Centre for Health and Related Research, The University of Sheffield, Sheffield, UK.
Judith Garcia-AymerichBarcelona Institute for Global Health (ISGlobal), Barcelona, Spain.ORCID https://orcid.org/0000-0002-7097-4586
Amy AuerEuropean Respiratory Society, Lausanne, Switzerland.
Christopher CarrollSheffield Centre for Health and Related Research, The University of Sheffield, Sheffield, UK.
Emma SimpsonSheffield Centre for Health and Related Research, The University of Sheffield, Sheffield, UK.
Pippa PowellEuropean Lung Foundation, Sheffield, UK.ORCID https://orcid.org/0000-0003-1828-8332
Lauren AndersonFreelance Communications Consultant, Sheffield, UK.
Guy JoosDepartment of Internal Medicine and Pediatrics, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.ORCID https://orcid.org/0000-0002-3149-9444

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Our systematic evidence map aimed to identify lung-related epidemiological estimates to populate the International Respiratory Coalition's Lung Facts website. We highlight important evidence gaps, suggest how they could be filled, and provide bespoke societal cost estimates to inform resource allocation. Methods: We examined 14 lung conditions across 53 World Health Organization Europe countries, seeking incidence, prevalence, mortality, years of life lost, years lived with disability, and disability-adjusted life year (DALY) estimates by age/sex. Global Burden of Disease (GBD) study estimates were obtained for nine GBD-included lung conditions: asthma, COPD, interstitial lung disease and pulmonary sarcoidosis, lower respiratory infections, lung cancer/tracheal, bronchus and lung cancer, tuberculosis, mesothelioma, COVID-19 and pulmonary arterial hypertension. Systematic searches of bibliographic databases were necessary for five non-GBD-included lung conditions: cystic fibrosis, obstructive sleep apnoea (OSA), influenza, alpha-1 antitrypsin deficiency (A1AD) and bronchiectasis. All-age country-specific DALY estimates were multiplied by gross domestic product per capita as a proxy for a country's wealth and prosperity to estimate societal costs. Results: Complete data for nine lung conditions for all countries were extracted from GBD, enabling societal cost estimation. Significant gaps were found for A1AD (only prevalence for 24 countries) and bronchiectasis (incidence, prevalence and mortality for between one and five countries), with more, but incomplete, estimates for cystic fibrosis, OSA and influenza. Conclusions: More epidemiological evidence is required for A1AD, bronchiectasis, cystic fibrosis, OSA, and influenza. Inclusion in the GDB study could help address these gaps. Lung Facts provides comprehensive lung-related epidemiological and societal cost estimates covering 53 countries to support policy-makers advocating for respiratory interventions.

Identifiers

PMID42376020
PMCPMC13312043

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.