Evidence map›Paper›PMID 42375984›Full record

ArticleOpen veterinary journal2026

The laxative efficacy of a mixed extract of

Amaq Fadholly, Siti Sadiah, Rudi Heryanto, Maharani Kartika Ramadhan

Abstract read
In one paragraph

Article in Open veterinary journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amaq FadhollyDivision of Pharmacology and Toxicology, School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, Indonesia.
Siti SadiahDivision of Pharmacology and Toxicology, School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, Indonesia.
Rudi HeryantoDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia.
Maharani Kartika RamadhanDoctoral Program in Animal Biosciences, Department of Biology, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The treatment of constipation with contemporary medications is costly and has a significant risk of adverse effects. Aim: This study evaluated the combined efficacy of the ethanolic leaf extract of Methods: Rats had constipation induced by an oral administration of loperamide (3 mg/kg BW) for 6 days, followed by three control groups assessment (normal, negative, positive which treated bisacodyl), and three treatment groups of the leaf extract of Results: All groups of the treatment demonstrated that oral administration of 50-100 mg/kg of the leaf extract combination demonstrated significant laxative activity, as reflected by improved gastrointestinal transit. Conclusion: The leaf extract combination of

Indexed as

CassiaConstipationLaxativesPlantagoPlant ExtractsAnimalsGastrointestinal TransitLoperamideMalePlant LeavesRatsRats, Sprague-DawleyLaxativesLoperamidePlant ExtractsCassia alataHerbsLaxativePlantago major.

Identifiers

PMID42375984
PMCPMC13314007

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.