ArticleOpen veterinary journal2026
Determination of the efficacy of red ginger (
Article in Open veterinary journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Background: Aim: This study evaluated the efficacy of red ginger extract against the Internal transcribed spacer 1 (ITS1) gene expression of Methods: Male mice were divided into five groups: Healthy Control, Infected Control (IC), Positive Drug Control, and treatment groups receiving red ginger extract at 30, 45, and 60 mg/kg BW. Parasitemia was monitored daily, and parasite load was measured using ITS1-targeted quantitative polymerase chain reaction (ΔΔCq). Liver histopathology was scored for edema, necrosis, hemorrhage, fatty degeneration, and inflammatory infiltration. Survival was analyzed using Kaplan-Meier curves and the log-rank test. Data were analyzed using one-way ANOVA or Kruskal-Wallis test ( Results: Ethanol-extracted red ginger reduced ITS1 gene expression and improved liver histology in a dose-dependent manner. The IC showed hepatocyte degeneration, necrosis, and inflammation, whereas treatment groups exhibited improved hepatocyte structure, reduced inflammation, and normalized sinusoids, especially at 60 mg/kg BW. Survival was highest in the 60 mg/kg BW group. All differences were statistically significant ( Conclusion: Red ginger extract is a promising natural therapeutic agent against
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