Evidence map›Paper›PMID 42375853›Full record

ArticleFrontiers in cardiovascular medicine2026

Association of serum coiled-coil domain containing protein 11 levels with coronary artery disease.

Jie Gao, Hongping Wang, Wenjun Wang, WenYing Hu, PengYong Yan, Jun Lu, ZongJun Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jie Gao *Department of Endocrinology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Hongping Wang *Department of Endocrinology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Wenjun WangDepartment of Endocrinology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
WenYing HuDepartment of Cardiology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
PengYong YanDepartment of Cardiology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jun LuDepartment of Endocrinology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
ZongJun LiuDepartment of Cardiology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to assess the association between circulating levels of coiled coil domain containing protein 11 (CCDC11) and coronary artery disease (CAD). Methods: A total of 266 patients diagnosed with CAD and 95 controls were enrolled in our center from January 2024 to December 2024. The CAD cohort was further stratified into three subgroups based on the number of affected coronary vessels: the single-vessel group ( Results: Median serum CCDC11 amounts were significantly elevated in the CAD group compared to controls (20.4 vs. 13.8 ng/mL, Conclusions: Elevated serum levels of CCDC11 were positively associated with both the presence and severity of CAD, suggesting that CCDC11 may serve as a novel and clinically valuable biomarker for CAD.

Indexed as

biomarkercardiovascular diseasecoiled coil domain containing protein 11 (CCDC11)coronary artery diseaseinflammation

Identifiers

PMID42375853
PMCPMC13310670

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.