Evidence map›Paper›PMID 42375820›Full record

ArticleFrontiers in computational neuroscience2026

AI-driven neuroanalytic modeling for mental health: multichannel CNN-based autism spectrum disorder detection via facial pattern analysis.

Narinder Kaur, Prabhdeep Singh, Kirandeep Singh, Jawad Khan, Dildar Hussain, Yeong Hyeon Gu, Reem Aljuaidi, Naif Waheb Rajkhan

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Article in Frontiers in computational neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Narinder KaurDepartment of Computer Science and Engineering, Chandigarh University, Mohali, India.
Prabhdeep SinghDepartment of Computer Science and Engineering, Graphic Era (Deemed to be University), Dehradun, India.
Kirandeep SinghDepartment of Computer Science and Engineering, Chitkara University, Rajpura, India.
Jawad KhanSchool of Computing, Gachon University, Seongnam, Republic of Korea.
Dildar HussainDepartment of AI and Data Science, Sejong University, Seoul, Republic of Korea.
Yeong Hyeon GuDepartment of AI and Data Science, Sejong University, Seoul, Republic of Korea.
Reem AljuaidiDepartment of Information System, College of Computer Engineering and Science, Prince Sattam Bin Abdalaziz University, Al-Kharj, Saudi Arabia.
Naif Waheb RajkhanDepartment of Computer Science, Faculty of Computing and Information Technology, King Abdulaziz University, Jeddah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by abnormal brain connections, impaired cognitive functions, and dysfunctional behaviors, which, in mental health, is a major challenge to diagnose at an early age. Recent developments in Artificial Intelligence (AI) and computational neuroscience have made it possible to use neuroanalytic methods to identify subtle patterns related to brain disorders. Inspired by this, this study investigates facial pattern analysis as a non-invasive surrogate biomarker. Methods: A neuroanalytic deep-learning model is suggested on the basis of a Modified Histogram of Oriented Gradients-based Multichannel Convolutional Neural Network (MHMCNN). The technique comprises three steps, that is, (i) preprocessing and normalization of facial images, (ii) extraction of discriminative neuro-inspired features based on modified HOG descriptors, and (iii) multichannel CNN-based classification to discover complex structural and micro-pattern variations. The model is trained and tested on a publicly accessible facial autism dataset, and the performance of the model is tested using Results: The proposed MHMCNN framework achieved a validation accuracy of 98% and a test accuracy of 96.2%, demonstrating strong generalization capability for ASD facial image classification. The model attained a training accuracy of 99.8%, indicating effective feature learning during optimization. The combination of handcrafted feature descriptors and deep learning improves the feature representation and the strength of classification. Experimental findings support the enhanced generalization and stable recognition of ASD-related patterns. Discussion: The results emphasize the possible application of AI and computational neuroscience in neuroanalytic pattern detection in mental health diagnostics. The proposed solution offers a cost-effective and scalable solution to early screening of ASD by allowing observable facial characteristics to be related to underlying neurodevelopmental features. The work has helped in filling the gap between the phenotypic observations and the diagnosis of the disorder of the brain. Future studies will target the use of multimodal integration of neuroimaging and behavioral data to enhance understanding and clinical utility. Conclusion: This research introduces a new combination of AI and neuroanalytic principles to detect ASD that can further advance computational neuroscience-based mental health diagnostics. The suggested framework offers a scalable and affordable outcome of early screening and future expansion to multimodal frameworks of neuroimaging and behavioral data to increase clinical utility and interpretation.

Indexed as

autism spectrum disorder (ASD)brain disorder detectioncomputational neurosciencefacial pattern analysisfeature extractionmental health diagnosisneuroanalytic artificial intelligence

Identifiers

PMID42375820
PMCPMC13310917

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