Evidence map›Paper›PMID 42375782›Full record

ArticleFrontiers in nutrition2026

Phase angle as a prognostic nutritional marker for survival in nasopharyngeal carcinoma patients undergoing chemoradiotherapy: a prospective cohort study.

Zhang Yanxin, Jiang Jiaping, Liang Limin, Huang Xiaojun, Yang Guirong, Li Wei, Tang Qiuhong, Wei Lina, Chen Xin, Lu Jiamei

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In one paragraph

Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Zhang Yanxin *Department of Radiotherapy, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Jiang Jiaping *Department of Radiotherapy, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Liang Limin *Department of Radiotherapy, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Huang Xiaojun *Department of Radiotherapy, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Yang GuirongDepartment of Radiotherapy, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Li WeiDepartment of Radiotherapy, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Tang QiuhongDepartment of Radiotherapy, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Wei LinaDepartment of Radiotherapy, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Chen XinDepartment of Radiotherapy, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Lu JiameiDepartment of Radiotherapy, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Conventional nutritional indicators have limitations in predicting outcomes for nasopharyngeal carcinoma (NPC) patients undergoing chemoradiotherapy. Phase angle (PA), a bioelectrical impedance-derived measure of cellular integrity, has emerged as a prognostic marker in various malignancies but remains understudied in NPC. This study investigated whether PA provides superior prognostic information for overall survival (OS) compared to conventional indicators. Methods: In this prospective cohort study, 380 newly diagnosed NPC patients scheduled for chemoradiotherapy were enrolled. PA was measured using InBody S10. Nutritional status was assessed via body mass index (BMI), serum albumin, and the Patient-Generated Subjective Global Assessment (PG-SGA). OS was the primary endpoint. For Kaplan-Meier visualization, patients were stratified by the median PA value. Multivariable Cox regression and time-dependent ROC analyses were performed. Results: Over a median 60-month follow-up, 27 deaths (7.1%) occurred. PA showed significant correlations with BMI (r = 0.512, Conclusion: PA may be an independent prognostic factor for newly diagnosed NPC patients undergoing chemoradiotherapy. These findings may support its potential utility in baseline risk assessment, though validation in larger cohorts is warranted.

Indexed as

chemoradiotherapynasopharyngeal carcinoma phase anglenutritional markerprognosissurvival

Identifiers

PMID42375782
PMCPMC13310778

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