ArticleCentral European journal of urology2026
Differences in pentafecta outcome between on-clamp and off-clamp robotic partial nephrectomy.
Article in Central European journal of urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Robotic partial nephrectomy (RAPN) can be considered the gold standard for the treatment of localized renal tumors (cT1-T2a). The on-clamp approach is considered safer for complex tumors, but the off-clamp approach is constantly growing, offering advantages for renal function. Material and methods: We enrolled 517 patients underwent RAPN between 1/2020 and 12/2023 and we divided in two groups: A (on-clamp) and B (off-clamp). We analyzed the individual parameters of the pentafecta outcomes, so absence of complications, negative surgical margins (PSMs), and warm ischemia period shorter than 25' or zero ischemia, >90% preservation of estimated glomerular filtration rate (eGFR) and no stage progression of chronic kidney disease (CKD) at 1-year follow-up, and finally the overall results. Results: The duration of surgery was significantly longer in group A (120' vs 90') (p <0.001). The median value for duration of warm ischemia was 16 minutes. Postoperative complications occurred in 22 cases (4.2%). Although the frequency of anemia was higher in Group B, in relation to the total number of procedures, no statistically significant difference was found (p = 0.36), neither for PSMs rate (p = 0.73). The achievement of pentafecta outcomes in group A and B was 79.7% and 91.2%, respectively (p ≤0.001). In patients who have undergone ischemia, the duration of clamping is correlated with the increase in postoperative creatinine (p <0.001). Conclusions: Off-clamp approaches show better results in pentafecta outcomes and to reduce the risk of increased creatinine in the post-operative course, although they require greater surgical skill but offer shorter execution times.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.