ArticleNAM journal2025
GenoITS: Implementation of an Integrated Testing Strategy workflow for genotoxicity using QSAR-based tools.
Article in NAM journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Genotoxic Damage and microRNA Dysregulation in Firefighters: An Integrated Biomonitoring Case Study.Journal of xenobiotics · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To assess the potential impact of chemical substances on human health and the environment, and to ensure the safety of chemicals, the EU's REACH regulation requires registrants of chemicals to undertake a battery of tests to fulfil Standard Information Requirements. These tests raise two main concerns, (1) the economic burden due to the resources needed to perform the tests, both in materials and time invested, and (2) the ethical considerations of using animal testing. For this reason, nowadays the regulatory agencies encourage registrants to minimize the number of experiments performed on animals (3Rs). In this work we have developed an exclusively computational Integrated Testing Strategy to assess the genotoxicity of chemicals. A complete set of data of assays for gene mutation and cytogenotoxicity (in bacteria,
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.