Evidence map›Paper›PMID 42375535›Full record

ArticleiScience2026

An exploratory study of circulating cell-free mRNAs across colorectal cancer stages.

Thibault Mazard, Marie Grosgeorges, Laura Veyrie, Simon Thezenas, Brice Pastor, Ekaterina Pisareva, Gérald Lossaint, Evelyne Lopez-Crapez, Marc Ychou, Alain R Thierry and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Thibault MazardIRCM, University Montpellier, ICM, INSERM, CNRS Montpellier, Campus Val d'Aurelle 208 avenue des Apothicaires, 34298, Montpellier cedex 5, France.
Marie GrosgeorgesIRCM, University Montpellier, ICM, INSERM, CNRS Montpellier, Campus Val d'Aurelle 208 avenue des Apothicaires, 34298, Montpellier cedex 5, France.
Laura VeyrieIRCM, University Montpellier, ICM, INSERM, CNRS Montpellier, Campus Val d'Aurelle 208 avenue des Apothicaires, 34298, Montpellier cedex 5, France.
Simon ThezenasICM, Institut du Cancer de Montpellier, Campus Val d'Aurelle 208 avenue des Apothicaires, 34298, Montpellier cedex 5, France.
Brice PastorIRCM, University Montpellier, ICM, INSERM, CNRS Montpellier, Campus Val d'Aurelle 208 avenue des Apothicaires, 34298, Montpellier cedex 5, France.
Ekaterina PisarevaIRCM, University Montpellier, ICM, INSERM, CNRS Montpellier, Campus Val d'Aurelle 208 avenue des Apothicaires, 34298, Montpellier cedex 5, France.
Gérald LossaintICM, Institut du Cancer de Montpellier, Campus Val d'Aurelle 208 avenue des Apothicaires, 34298, Montpellier cedex 5, France.
Evelyne Lopez-CrapezIRCM, University Montpellier, ICM, INSERM, CNRS Montpellier, Campus Val d'Aurelle 208 avenue des Apothicaires, 34298, Montpellier cedex 5, France.
Marc YchouIRCM, University Montpellier, ICM, INSERM, CNRS Montpellier, Campus Val d'Aurelle 208 avenue des Apothicaires, 34298, Montpellier cedex 5, France.
Alain R ThierryIRCM, University Montpellier, ICM, INSERM, CNRS Montpellier, Campus Val d'Aurelle 208 avenue des Apothicaires, 34298, Montpellier cedex 5, France.
Corinne PrévostelIRCM, University Montpellier, ICM, INSERM, CNRS Montpellier, Campus Val d'Aurelle 208 avenue des Apothicaires, 34298, Montpellier cedex 5, France.
Philippe BlacheIRCM, University Montpellier, ICM, INSERM, CNRS Montpellier, Campus Val d'Aurelle 208 avenue des Apothicaires, 34298, Montpellier cedex 5, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated circulating mRNAs (B2M, TIMP-1, CLU, SERPINE1, GAL3, and S100A9) as potential biomarkers for colorectal cancer (CRC). Plasma levels were measured in CRC patients (stages I-IV,

Indexed as

cancerdiagnosticsmedical biochemistryoncology

Identifiers

PMID42375535
PMCPMC13310942

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.