Evidence map›Paper›PMID 42375451›Full record

ArticleOpen veterinary journal2026

Does the spleen regenerate in rabbits after partial splenectomy?

Asmaa Bouknine, Mira Chiraoui, Abdelhak Bouknine, Hemida Houari, Sidi Ali Selmani

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Article in Open veterinary journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Asmaa BouknineInstitute of Veterinary Science, University of Blida, Blida, Algeria.
Mira ChiraouiInstitute of Veterinary Sciences, Ibn Khaldoun University of Tiaret, Tiaret, Algeria.
Abdelhak BouknineLaboratory of Biodiversity, Health and Resource Valorization, Faculty of Natural and Life Sciences, Ibn Khaldoun University of Tiaret, Tiaret, Algeria.
Hemida HouariInstitute of Veterinary Sciences, Ibn Khaldoun University of Tiaret, Tiaret, Algeria.
Sidi Ali SelmaniInstitute of Veterinary Science, University of Blida, Blida, Algeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The spleen plays a vital role in the regulation of immunity and blood complete splenectomy can increase vulnerability to infection, whereas partial splenectomy preserves function. However, the ability of residual tissue to regenerate remains uncertain. Aim: Hematological and histological evaluation of spleen regeneration following partial splenectomy in Algerian rabbits. Methods: Fifteen adult male rabbits were divided into three groups, with five animals in each group. Clinical evaluation, hematological analysis, and histological examination were performed to assess the extent of splenic regeneration following partial splenectomy. Results: All animals recovered uneventfully. On day 15, mild anemia and inflammatory changes were observed. By day 30, the splenic tissue showed reorganization with active lymphoid follicles, angiogenesis, and restored hematologic values. Conclusion: Partial splenectomy in rabbits allows for structural and functional regeneration within 1 month, indicating that it a safe and effective approach to preserve splenic activity.

Indexed as

RegenerationSpleenSplenectomyAnimalsMaleRabbitsHistologyPartial splenectomyRabbitRegenerationSpleen

Identifiers

PMID42375451
PMCPMC13313890

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.