ArticleOpen veterinary journal2026
Comparative effects of syngeneic graft and xenograft blood for hemolytic anemia modeling in dogs.
Article in Open veterinary journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Background: Hemolytic anemia (HA) involves premature red blood cell (RBC) destruction and often occurs in dogs as immune-mediated HA (IMHA) and hemolytic transfusion reactions (HTRs). Developing an animal model is crucial for studying its mechanisms. Syngeneic grafts or xenograft blood can be used experimentally to induce hemolytic and autoimmune responses through self-antigen mimicry. Aim: This study aimed to examine the comparative effects of syngeneic graft and xenograft blood on HA induction in mice. Methods: There were three groups ( Results: The results showed that the xenograft blood group had higher ( Conclusion: The research concluded that syngeneic graft blood induced a HTRs model, and xenograft blood induced an IMHA-like model.
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