Evidence map›Paper›PMID 42375173›Full record

ArticleOncology letters2026

Bioinformatics analysis of proteins in the complement and coagulation cascades in colon cancer: Discovering the potential biomarker SERPINA1.

Da Lian, Daixin Hou, Kunpeng Liu, Hao Jiang, Pengyu Xie

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Da LianDepartment of Clinical Medicine, School of Clinical Medicine, Jiamusi University, Jiamusi, Heilongjiang 154007, P.R. China.
Daixin HouDepartment of Clinical Medicine, School of Clinical Medicine, Jiamusi University, Jiamusi, Heilongjiang 154007, P.R. China.
Kunpeng LiuDepartment of Clinical Medicine, School of Clinical Medicine, Jiamusi University, Jiamusi, Heilongjiang 154007, P.R. China.
Hao JiangDepartment of Clinical Medicine, School of Clinical Medicine, Jiamusi University, Jiamusi, Heilongjiang 154007, P.R. China.
Pengyu XieDepartment of Biology, School of Basic Medicine, Jiamusi University, Jiamusi, Heilongjiang 154007, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complement system, a core component of innate immunity, plays a key role in the tumorigenesis and progression of colon cancer. Although dysregulation in proteins associated with the complement and coagulation cascades (CCC) pathway has been identified in colon cancer, comprehensive investigations in this area are still scarce. In the present study, differential expression analysis was performed on colon adenocarcinoma (COAD) obtained from the GEPIA2 database (www.gepia2.cancer-pku.cn), to compare gene expression profiles between tumor tissues and paired adjacent normal tissues. A threshold of |log

Indexed as

bioinformaticscolon cancercomplement and coagulation cascadesserpin family A member 1

Identifiers

PMID42375173
PMCPMC13311930

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.