Evidence map›Paper›PMID 42375160›Full record

ArticleGynecologic oncology reports2026

Gestational trophoblastic neoplasia treated with low-dose induction chemotherapy despite prognostic score < 13: a case report.

Patrick Marta, Katelyn B Furey, Hadi Erfani, Nathan Yee, Laila I Muderspach, Koji Matsuo, Anna L Beavis

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Gynecologic oncology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Patrick MartaHarbor-UCLA Medical Center, 1000 W Carson St, Torrance, CA 90502, United States of America.
Katelyn B FureyLos Angeles General Medical Center, 1200 N State St, Los Angeles, CA 90033, United States of America.
Hadi ErfaniLos Angeles General Medical Center, 1200 N State St, Los Angeles, CA 90033, United States of America.
Nathan YeeHarbor-UCLA Medical Center, 1000 W Carson St, Torrance, CA 90502, United States of America.
Laila I MuderspachLos Angeles General Medical Center, 1200 N State St, Los Angeles, CA 90033, United States of America.
Koji MatsuoKeck School of Medicine, 1975 Zonal Ave., Los Angeles, CA 90033, United States of America.
Anna L BeavisHarbor-UCLA Medical Center, 1000 W Carson St, Torrance, CA 90502, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Gestational trophoblastic neoplasia (GTN) can cause significant morbidity and mortality if not appropriately recognized and treated. Low-dose induction chemotherapy is recommended for "ultra-high risk" GTN- defined as prognostic score ≥ 13 - to prevent mortality from hemorrhage that occurs when tumors respond rapidly. Case: A 22-year-old patient presented with hemoptysis due to pulmonary metastases from GTN, but with WHO score < 13. A multi-disciplinary care team began treatment with low-dose induction chemotherapy to prevent worsening pulmonary hemorrhage. While she required intubation to complete induction chemotherapy, she did not suffer further pulmonary hemorrhage during treatment. Conclusion: Low-dose induction chemotherapy should be considered as treatment for patients with GTN and pulmonary metastasis causing hemorrhage even if WHO score is <13.

Indexed as

Gestational trophoblastic neoplasiaInduction chemotherapyPulmonary hemorrhageWHO score

Identifiers

PMID42375160
PMCPMC13312480

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.