ArticleBiomolecules & therapeutics2026
TRPV4 Activation Promotes Hair Growth via TSLP Signaling in the Skin.
Article in Biomolecules & therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 authors.
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Abstract
Hair follicle cycling is regulated by complex signaling networks that coordinate stem cell activation and quiescence. Although transient receptor potential vanilloid 4 (TRPV4) is expressed in the skin and implicated in cutaneous physiology, its role in hair growth remains unclear. Here, we investigated the contribution of TRPV4 activation to hair growth and its relationship with thymic stromal lymphopoietin (TSLP). Pharmacological activation of TRPV4 using GSK1016790A significantly promoted hair regrowth and elongation in mice, whereas TRPV4 inhibition attenuated these effects. Consistently,
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