Evidence map›Paper›PMID 42374906›Full record

ArticleAngewandte Chemie (International ed. in English)2026

Metal-Organic Framework-Gated Biocatalysis Enables Triggered Depolymerization of Melt-Processed Polyesters.

Shitong Cui, Jing Tian, Mengyu Zhu, Zihan Liu, Yufei Cao, Yu Liu, Yuxiao Feng, Wanghui Xu, Weijian Lai, Hongyi Yang and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Shitong CuiDepartment of Chemical Engineering, Ministry of Education, Key Lab for Industrial Biocatalysis, Tsinghua University, Beijing, China.
Jing TianDepartment of Chemical Engineering, Ministry of Education, Advanced Materials Laboratory, Tsinghua University, Beijing, China.
Mengyu ZhuDepartment of Chemical Engineering, Ministry of Education, Key Lab for Industrial Biocatalysis, Tsinghua University, Beijing, China.
Zihan LiuSchool of Energy and Environmental Engineering, University of Science and Technology, Beijing, China.
Yufei CaoLab of Applied Biocatalysis, School of Food Science and Technology, South China University of Technology, Guangzhou, China.ORCID 0000-0002-4742-4009
Yu LiuDepartment of Chemical Engineering, Ministry of Education, Key Lab for Industrial Biocatalysis, Tsinghua University, Beijing, China.
Yuxiao FengDepartment of Chemical Engineering, Ministry of Education, Key Lab for Industrial Biocatalysis, Tsinghua University, Beijing, China.
Wanghui XuNovozymes (China) Investment Co. Ltd, Beijing, China.
Weijian LaiNovozymes (China) Investment Co. Ltd, Beijing, China.
Hongyi YangNovozymes (China) Investment Co. Ltd, Beijing, China.
Jun XuDepartment of Chemical Engineering, Ministry of Education, Advanced Materials Laboratory, Tsinghua University, Beijing, China.
Baohua GuoDepartment of Chemical Engineering, Ministry of Education, Advanced Materials Laboratory, Tsinghua University, Beijing, China.
Lin QiuSchool of Energy and Environmental Engineering, University of Science and Technology, Beijing, China.
Zhenzhong YangDepartment of Chemical Engineering, Ministry of Education, Key Lab for Industrial Biocatalysis, Tsinghua University, Beijing, China.
Paolo FalcaroInstitute of Physical and Theoretical Chemistry, Graz University of Technology, Graz, Austria.ORCID 0000-0001-5935-0409
Jun GeDepartment of Chemical Engineering, Ministry of Education, Key Lab for Industrial Biocatalysis, Tsinghua University, Beijing, China.ORCID 0000-0001-5503-8899

Funding

Beijing Natural Science Foundation Z240030Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China JYB2025XDXM509National Natural Science Foundation of China 22425803Shenzhen Science and Technology Program KCXFZ20240903093102004Tsinghua University Initiative Research Program 2023Z02ORD001
6 · The paper itself

Abstract

Controlling biocatalytic activity in melt-processed polymers is a central challenge for triggered depolymerization, because enzymes deactivate at melt-extrusion temperatures. Here, metal-organic framework-gated biocatalysis, achieved by encapsulating enzymes within zeolitic imidazolate framework-8 (ZIF-8), preserves > 85% activity after 2 min at 180°C while regulating substrate access. Enzyme@ZIF-8 biocomposite production scales to ∼50 kg day

Indexed as

Metal-Organic FrameworksPolyestersBiocatalysisLipasePolymerizationZeolitesLipaseMetal-Organic FrameworksPolyesterspoly(lactide)Zeolitesenzyme‐metal cooperative catalysisenzyme‐MOF compositesmelt extrusionmetal–organic frameworks (MOFs)polyester degradation

Identifiers

PMID42374906
PMCPMC13528521

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.