ArticlePest management science2026
Hypogin-derived N-cinnamoylated peptide as a promising green fungicide against peanut southern blight caused by Sclerotium rolfsii.
Article in Pest management science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPeanut southern blight, caused by Sclerotium rolfsii, severely reduces yield and quality. The overuse of chemical fungicides accelerates resistance development and raises environmental concerns, highlighting the necessity for eco-friendly alternatives. Hypogin is an endogenous peanut peptide with broad-spectrum antifungal activity. This study aims to identify the active centers of hypogin and evaluate the antifungal activity and preliminary mechanisms of its derived peptides.
resultsSeven hypogin-derived peptides (series I) and two cinnamic acid conjugates (series II) were synthesized. Among these, II-1 (cinnamic-KSPY-NH
conclusionHypogin-derived peptide II-1 exhibits significant antifungal activity and low toxicity, making it a promising candidate for a green fungicide in the management of peanut southern blight. © 2026 Society of Chemical Industry.
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