ArticleInternational journal of retina and vitreous2026
Comparison of prognostic outcomes in vitrectomy for myopic foveoschisis with foveal detachment: air tamponade versus no-air tamponade.
Article in International journal of retina and vitreous, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo compare the efficacy of pars plana vitrectomy with or without air tamponade for patients with myopic foveoschisis (MFS) and foveal detachment (FD).
methodsForty-seven patients (47 eyes) with MFS and FD who underwent PPV with fovea-sparing internal limiting membrane peeling were included in this retrospective analysis. Patients were divided into air-tamponade (n = 21) and no-air-tamponade (n = 26) groups. Central foveal thickness (CFT), external limiting membrane (ELM) / ellipsoid zone (EZ) integrity, best-corrected visual acuity (BCVA), and incidence of complications were compared.
resultsIn longitudinal analysis, the air-tamponade group had significantly faster CFT reduction at 1 week and 1 month (both P < 0.05). By 3 and 12 months, the CFT values were comparable between groups. Time to foveal reattachment was shorter with air tamponade (P < 0.001). The ELM and EZ integrity were compared at 12 months (both P > 0.05). Postoperative BCVA showed significant improvement from baseline at 3 and 12 months in both groups (P < 0.05). The time-by- tamponade type interaction at 3 and 12 months was not significantly different on BCVA in multivariable model (P > 0.05). Baseline diameter of FD was identified as an independent risk factor of 12-month BCVA by multivariable analysis. Complication rates, including postoperative macular hole, macular hole with retinal detachment, and transient aggravation, did not significantly differ between groups.
conclusionAir tamponade accelerated early anatomical recovery in MFS with FD, but both tamponade types achieved comparable long-term anatomical and visual outcomes. Baseline FD diameter was the independent predictor of visual outcome. CLINICAL TRIAL NUMBER: Not applicable.
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